Preoperative Serum Fibrinogen Level Predicts Postoperative Pulmonary Complications After Lung Cancer Resection Suk-Won Song, MD, Hyun-Sung Lee, MD, Moon.

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Preoperative Serum Fibrinogen Level Predicts Postoperative Pulmonary Complications After Lung Cancer Resection Suk-Won Song, MD, Hyun-Sung Lee, MD, Moon Soo Kim, MD, Jong Mog Lee, MD, Jee Hee Kim, MD, Byung-Ho Nam, PhD, Jae Ill Zo, MD, PhD The Annals of Thoracic Surgery Volume 81, Issue 6, Pages 1974-1981 (June 2006) DOI: 10.1016/j.athoracsur.2006.01.032 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Survival of patients in the no–postoperative pulmonary complications (PPCs) group and the PPCs group. (A) Overall survival at 3 years was 68.2% in the no-PPCs group, and 38.8% in the PPCs group (p < 0.0001). (B) Disease-free survival at 3 years was 60.2% in the no-PPCs group, and 56.2% in the PPCs group (p = 0.232). The Annals of Thoracic Surgery 2006 81, 1974-1981DOI: (10.1016/j.athoracsur.2006.01.032) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Survival of patients according to tumor stage in the no–postoperative pulmonary complications (PPCs) group and the PPCs group. (A) Overall survival at 1 and 3 years was, respectively, 94.8% and 81.9% in the no-PPCs group and 84.6% and 43.0% in the PPCs group in the early stage (stage I and II; p = 0.001). (B) Disease-free survival at 1 and 3 years was, respectively, 85.7% and 72.8% in the no-PPCs groups and 77.0% and 65.1% in the PPCs group in the early stage (stage I and II; p = 0.165). (C) Overall survival at 1 and 2 years was, respectively, 88.0% and 68.7% in the no-PPCs group and 66.5 and 32.8% in the PPCs group in the advanced stage (stage III and IV; p = 0.001). (D) Disease-free survival at 1 and 2 years was, respectively, 61.6% and 43.6% in the no-PPCs groups and 61.6 and 39.6% in the PPCs group in the advanced stage (stage III and IV; p = 0.621). The Annals of Thoracic Surgery 2006 81, 1974-1981DOI: (10.1016/j.athoracsur.2006.01.032) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Cumulative mortality during the follow-up from cancer-unrelated causes after lung resection in the no–postoperative pulmonary complications (PPCs) group and the PPCs group (p < 0.0001). The Annals of Thoracic Surgery 2006 81, 1974-1981DOI: (10.1016/j.athoracsur.2006.01.032) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions