Impact of Negative Clinical Trial Results for Vertebroplasty on Vertebral Augmentation Procedure Rates Fabrice Smieliauskas, PhD, Sandi Lam, MD, MBA,

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Impact of Negative Clinical Trial Results for Vertebroplasty on Vertebral Augmentation Procedure Rates Fabrice Smieliauskas, PhD, Sandi Lam, MD, MBA, David H. Howard, PhD Journal of the American College of Surgeons Volume 219, Issue 3, Pages 525-533.e1 (September 2014) DOI: 10.1016/j.jamcollsurg.2014.03.047 Copyright © 2014 American College of Surgeons Terms and Conditions

Figure 1 Common spine procedure rates per 100,000 adults. Procedure rates per 100,000 adults in quarter 1 (Q1) 2005 are: vertebroplasties, 3.8; kyphoplasties, 8.1; spinal fusions, 41.7; and spinal discectomies, 24.9. All rates are seasonally adjusted. The TRIALS line indicates quarter before publication of vertebroplasty trials. The AAOS line indicates quarter before release of the American Academy of Orthopaedic Surgeons statement on vertebral augmentation procedures. Journal of the American College of Surgeons 2014 219, 525-533.e1DOI: (10.1016/j.jamcollsurg.2014.03.047) Copyright © 2014 American College of Surgeons Terms and Conditions

Figure 2 Vertebral augmentation procedure rates per 100,000 adults, by physician specialty. (A) Vertebroplasties; (B) kyphoplasties. Vertebroplasty procedure rates per 100,000 adults in quarter 1 (Q1) 2005 are: interventional radiologists, 2.3; other specialties, 1.3. Kyphoplasty procedure rates: interventional radiologists, 0.8; other specialties, 6.8. All rates are seasonally adjusted. The TRIALS line indicates quarter before publication of vertebroplasty trials. The AAOS line indicates quarter before release of American Academy of Orthopaedic Surgeons statement on vertebral augmentation procedures. Journal of the American College of Surgeons 2014 219, 525-533.e1DOI: (10.1016/j.jamcollsurg.2014.03.047) Copyright © 2014 American College of Surgeons Terms and Conditions