Schematic of the principles of mass spectrometry (MS).

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Presentation transcript:

Schematic of the principles of mass spectrometry (MS). Schematic of the principles of mass spectrometry (MS). Three basic modules for the interrogation of a sample containing analytes (eg, proteins) of interest are shown. 1. Source of ionizing radiation (eg, electrospray [ESI] or matrix-assisted laser desorption/ionization [MALDI]). 2. Mass analyzers that resolve ions based on their overall mass-to-charge (m/z) ratios. 3. A detector that processes ions signals to mass spectra. Xuefeng B. Ling, and Karl G. Sylvester Neoreviews 2011;12:e585-e591 ©2011 by American Academy of Pediatrics