Calciphylaxis The Lancet Volume 383, Issue 9922, (March 2014)

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Presentation transcript:

Calciphylaxis The Lancet Volume 383, Issue 9922, (March 2014) Qian Zhou, MD, Jakob Neubauer, MD, Johannes S Kern, MD, Prof Wolfgang Grotz, MD, Prof Gerd Walz, MD, Dr Prof Tobias B Huber, MD The Lancet Volume 383, Issue 9922, (March 2014) DOI: 10.1016/S0140-6736(14)60235-X Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure Clinical and histological presentation of calciphylaxis (A) Non-healing ulceration on the left lower leg with necrotic border. (B) Radiograph of the left lower leg with diffuse calcifications and stenoses of the arteries (arrows). (C) Histological examination of skin biopsy from the ulceration: calcific sclerosis and microthrombi within a small artery (haematoxylin and eosin stain, magnification ×200). (D) Calcium deposition of an artery (von Kossa stain, magnification ×200); calcium deposits are highlighted as dark granules (arrow). The Lancet 2014 383, DOI: (10.1016/S0140-6736(14)60235-X) Copyright © 2014 Elsevier Ltd Terms and Conditions