Direct-To-Consumer Genetic Testing

Background

What DTC Genetic Testing Has to Offer

Some Things to Keep in Mind About DTC Testing

Summary of Important Genetic Terms

Single Nucleotide Polymorphisms (SNPs)

SNPs (cont)

DTC Genetic Testing Is a Simple Process

Platforms for Detecting Variants

Scope of DTC Genetic Testing

23andMe Disease-Based DTC Genetic Tests/ FDA-Authorized*

4 Approaches to Understanding DTC Results

Real Diseases, Real Diagnoses

Gateway to Genomic Medicine

Evolving Field of DTC

Proceed With Caution in the Case of Third-Party Analyses

Patient Story Walt*

Patient Story Walt and DTC Genetic Testing Results

Walt’s Advice to Clinicians

PCP Perspective

Impact of Personal Genomics Study (PGEN)*

PGEN Results Cancer*

PGEN Results Health Behaviors

Scripps Study Psychological, Behavioral, and Clinical Effects of Risk

Scripps Study Psychological, Behavioral, and Clinical Effects of Risk (cont)

PCP and Patient Perspectives in Different Settings or Geographic Areas

Genetic Counselor Perspective

PCP Communication Tips

Role Playing—Common Situations With Patients Prepregnancy Planning

Role Playing—Common Situations With Patients Cancer

Role Playing—Common Situations With Patients An Uncommon Disorder

Concluding Remarks Common Genetic Screens

Concluding Remarks Data

Concluding Remarks Patient Engagement and Education

Concluding Remarks You Don’t Have to Be a Genetic Expert

Abbreviations