Volume 69, Issue 2, Pages (February 2016)

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Presentation transcript:

Volume 69, Issue 2, Pages 231-244 (February 2016) Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials Comparing a Single Immediate Instillation of Chemotherapy After Transurethral Resection with Transurethral Resection Alone in Patients with Stage pTa–pT1 Urothelial Carcinoma of the Bladder: Which Patients Benefit from the Instillation?  Richard J. Sylvester, Willem Oosterlinck, Sten Holmang, Matthew R. Sydes, Alison Birtle, Sigurdur Gudjonsson, Cosimo De Nunzio, Kikuo Okamura, Eero Kaasinen, Eduardo Solsona, Bedeir Ali-El-Dein, Can Ali Tatar, Brant A. Inman, James N’Dow, Jorg R. Oddens, Marek Babjuk  European Urology  Volume 69, Issue 2, Pages 231-244 (February 2016) DOI: 10.1016/j.eururo.2015.05.050 Copyright © 2015 European Association of Urology Terms and Conditions

Fig. 1 Effect of an immediate instillation on recurrence by patient characteristics. CI=confidence interval; EAU=European Association of Urology; EORTC=European Organization for Research and Treatment of Cancer; HG=high grade; HR=hazard ratio; LG=low grade; Rec=recurrence. European Urology 2016 69, 231-244DOI: (10.1016/j.eururo.2015.05.050) Copyright © 2015 European Association of Urology Terms and Conditions

Fig. 2 Time to first recurrence. European Urology 2016 69, 231-244DOI: (10.1016/j.eururo.2015.05.050) Copyright © 2015 European Association of Urology Terms and Conditions

Fig. 3 Time to first recurrence stratified by chemotherapy and study. CI=confidence interval; HR=hazard ratio; MRC=Medical Research Council. European Urology 2016 69, 231-244DOI: (10.1016/j.eururo.2015.05.050) Copyright © 2015 European Association of Urology Terms and Conditions

Fig. 4 Time to progression. European Urology 2016 69, 231-244DOI: (10.1016/j.eururo.2015.05.050) Copyright © 2015 European Association of Urology Terms and Conditions

Fig. 5 Duration of survival. European Urology 2016 69, 231-244DOI: (10.1016/j.eururo.2015.05.050) Copyright © 2015 European Association of Urology Terms and Conditions

Fig. 6 Time to death due to bladder cancer. European Urology 2016 69, 231-244DOI: (10.1016/j.eururo.2015.05.050) Copyright © 2015 European Association of Urology Terms and Conditions

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