International Journal of Surgery

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International Journal of Surgery Epidural analgesia for cytoreductive surgery with peritonectomy and heated intraperitoneal chemotherapy Federico Piccioni, Claudia Casiraghi, Luca Fumagalli, Shigeki Kusamura, Dario Baratti, Marcello Deraco, Flavio Arienti, Martin Langer International Journal of Surgery Volume 16, Pages 99-106 (April 2015) DOI: 10.1016/j.ijsu.2015.02.025 Copyright © 2015 Surgical Associates Ltd Terms and Conditions

Fig. 1 Verbal numerical scale (VNS) score at rest and on movement reported by patients post-operatively. The bands in the boxes represent the median value; bottom and top of the boxes stand for the 25th and 75th percentile; the ends of the whiskers are plotted according to the Tukey method. International Journal of Surgery 2015 16, 99-106DOI: (10.1016/j.ijsu.2015.02.025) Copyright © 2015 Surgical Associates Ltd Terms and Conditions

Fig. 2 Scatter plot of per-operative transfused fresh frozen plasma (FFP). Each dot represents the amount of FFP transfused to each patient. Non-transfused patients are not reported. Horizontal bars stand for median FFP transfused to the entire studied population. International Journal of Surgery 2015 16, 99-106DOI: (10.1016/j.ijsu.2015.02.025) Copyright © 2015 Surgical Associates Ltd Terms and Conditions

Fig. 3 Coagulation parameters and platelet count values measured before and after operation. Data are expressed as geometric mean and 95%CI. *P < 0.001 and §P < 0.05 compared to pre-operative values. Hb = Hemoglobin; PT = Prothrombine time; aPTT = Activated partial thromboplastin time; PLT = Platelets count; Pre-op = Pre-operative; Intra-op = Intra-operative. International Journal of Surgery 2015 16, 99-106DOI: (10.1016/j.ijsu.2015.02.025) Copyright © 2015 Surgical Associates Ltd Terms and Conditions

Fig. 4 Prothrombin time (PT-INR) values measured on the day of epidural catheter removal. Each patient is represented according to intentional (○) or accidental (×) catheter removal. International Journal of Surgery 2015 16, 99-106DOI: (10.1016/j.ijsu.2015.02.025) Copyright © 2015 Surgical Associates Ltd Terms and Conditions