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Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2016.96 Figure 3 Endoscopic images of the PEMR, underwater EMR and hybrid ESD–PEMR techniques Figure 3 | Endoscopic images of the PEMR, underwater EMR and hybrid ESD–PEMR techniques. a | A 13 cm non-granular LST circumferential polyp in the ascending colon. b | The post-resection defect following PEMR. c | Underwater EMR assisted by the Endocuff Vision device (Arc Medical Design Ltd, UK) for a 2cm recurrent flat polyp. d | The post-resection defect following underwater EMR. e | A 10cm rectal granular LST type polyp. f | The post-resection defect following hybrid ESD–PEMR using a ball-tipped FlushKnife (Fujifilm, Japan). EMR, endoscopic mucosal resection; ESD, endoscopic submucosal dissection; LST, laterally spreading tumour; PEMR, piecemeal endoscopic mucosal resection. Saunders, B. P. & Tsiamoulos, Z. P. (2016) Endoscopic mucosal resection and endoscopic submucosal dissection of large colonic polyps Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2016.96