Back to 2D Culture for Ground State of Intestinal Stem Cells

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Presentation transcript:

Back to 2D Culture for Ground State of Intestinal Stem Cells Mariko Shimokawa, Toshiro Sato Cell Stem Cell Volume 17, Issue 1, Pages 5-7 (July 2015) DOI: 10.1016/j.stem.2015.06.008 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Generation of Homogeneic Stem Cell Population In Vitro (A) In intestinal organoid culture, intestinal stem cells require niche signals from differentiated epithelium, and organoids are composed of both stem cells (green) and differentiated cells (gray). (B) A homogeneous intestinal stem cell population is generated using the ISCGS culture system. Intestinal epithelial colonies are composed of uniform intestinal stem cells (green) on fibroblast feeder layer (gray). Cell Stem Cell 2015 17, 5-7DOI: (10.1016/j.stem.2015.06.008) Copyright © 2015 Elsevier Inc. Terms and Conditions