DNA Replication
Why does DNA replicate? Cells copy genetic information before cell division so that each new cell has a complete set of DNA DNA replication occurs in the nucleus…WHY??
DNA Template
How does DNA replicate 1) UNWIND: Topoisomerase unwinds the coiled strands of DNA
2) UNZIP: DNA Helicase “unzips” the strands of DNA breaking the hydrogen bonds
3) HOLD OPEN: Single-Strand Binding proteins (SSBs) keep strands separated
4) BASE PAIRING: DNA polymerase III bonds free floating nucleotides with nucleotides from the parent strand
6) PROOFREAD: DNA Polymerase I proofreads new strand and backtracks to correct errors
5) JOINING NUCLEOTIDES: DNA ligase bonds those nucleotides together.
The result is 2 identical DNA molecules.
Each w/1 new strand & 1 old strand Called Semi-conservative replication
(Continuous Replication) (Place where replication begins) (Replication starts & stops)
DNA Replication Animation
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