Comparison of treatment strategies for patients with intestinal diffuse large B-cell lymphoma: surgical resection followed by chemotherapy versus chemotherapy.

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Comparison of treatment strategies for patients with intestinal diffuse large B-cell lymphoma: surgical resection followed by chemotherapy versus chemotherapy alone by Seok Jin Kim, Hye Jin Kang, Jin Seok Kim, Sung Yong Oh, Chul Won Choi, Soon Il Lee, Jong Ho Won, Min Kyoung Kim, Jung Hye Kwon, Yeung-Chul Mun, Jae-Yong Kwak, Jung Mi Kwon, In Gyu Hwang, Hyo Jung Kim, Jinny Park, Sukjoong Oh, Jooryung Huh, Young Hyeh Ko, Cheolwon Suh, and Won Seog Kim Blood Volume 117(6):1958-1965 February 10, 2011 ©2011 by American Society of Hematology

Survival outcomes were compared in patients with localized disease according to the treatment strategy. Survival outcomes were compared in patients with localized disease according to the treatment strategy. Surgical resection followed by chemotherapy produced significantly longer OS (A) and PFS (D) than chemotherapy alone. In patients treated with primary surgical resection for localized disease, the postoperative chemotherapy regimen, CHOP or R-CHOP, did not significantly affect OS (B) or PFS (E). In patients treated with chemotherapy alone, OS (C) and PFS (F) did not differ between patients treated with CHOP or R-CHOP. Seok Jin Kim et al. Blood 2011;117:1958-1965 ©2011 by American Society of Hematology

Comparison of survival outcomes in patients with disseminated disease according to the treatment strategy. Comparison of survival outcomes in patients with disseminated disease according to the treatment strategy. OS (A) and PFS (B) did not differ between the surgery/chemotherapy and chemotherapy groups. However, comparison according to the use of rituximab showed longer OS (C) and PFS (D) in patients treated with R-CHOP than in those treated with CHOP. Seok Jin Kim et al. Blood 2011;117:1958-1965 ©2011 by American Society of Hematology