modified from: cell division genes activated Short answer #2: What is this? After discussing with your group, describe this process: Write a one paragraph explanation of what you are seeing: 7 minutes! E2F kinase protein + ATP ------------> protein-P + ADP E2F cell division genes activated modified from:

1. Which of the following statements best fits as an analogy for a cell with a mutation in a tumor-suppressor gene?  A. The starter is broken. B. The gas pedal of a car does not work at all. C. The brake pedal of a car gets stuck while pushed down. D. The brake pedal of a car does not work at all. 2. Which of the following is true concerning oncogenes and tumor suppressor genes? A. mutations in proto-oncogenes cause mutations in tumor suppressor genes B. mutations in tumor suppressor genes are dominant to their normal alleles C. mutations that convert in proto-oncogenes to oncogenes are dominant to their normal alleles D. mutations in tumor suppressor genes cause mutations of proto-oncogenes to oncogenes

3. Which of the following can convert a proto-oncogene to an oncogene 3. Which of the following can convert a proto-oncogene to an oncogene?   A.  growth factor exposure B.  gene damage C.  pairing of the proto-oncogene with a tumor-suppressor gene D.  cyclin production 4.  The progress of the cell cycle is regulated by ______ and their dependent kinases.   A.  hormones B.  chromosomes C.  cyclins D.  endocrine signals

5. Which of the following sequence of cell-cycle phases is characteristic of eukaryotes?  A. G to S to M B. G1 to S to G2 to M to C C. S to M to C D. G1 to G2 to S to C E. G1 to G2 to G3 to S to C 6. In humans the diploid number of chromosomes is 46. The haploid number is 23. Prior to mitosis in the cell cycle, the cell is in the G2 phase. Which of the statements is true?  A. The homologous chromosomes are lined up on the equator. B. The homologous chromosomes have all been copied through DNA replication and are now sister chromatids. C. The homologous chromosomes have been pulled to their respective poles by the spindle apparatus. D. The homologous chromosomes have not been replicated yet. E. The is now in the haploid or 1n state.   7. Following S phase, a human cell would have how many pairs of sister chromatids and individual DNA molecules?  A. 23 pairs of sister chromatids and 46 individual DNA molecules B. 23 pairs of sister chromatids and 92 individual DNA molecules C. 46 pairs of sister chromatids and 46 individual DNA molecules D. 46 pairs of sister chromatids and 92 individual DNA molecules E. 46 pairs of sister chromatids and 184 individual DNA molecules

The Cell Cycle in an Animal Cell, a play in several acts The players: 1. Separase; 2. Cohesin; 3. A pair of homologous chromosomes (can exist in condensed of decondensed states); 4. Kinetochores; 5; Centrioles; Microtubules; 6. Securin; 7. Nuclear membrane Act I, in which (ignoring cell cycle checkpoints) key activities take place during the S phase of the cell cycle Act II, in which (ignoring cell cycle checkpoints) the cell readies itself for Mitosis Act III, in which (NOT ignoring the Anaphase [a.k.a Spindle] Checkpoint!) genetic material is separated to two poles of a dividing cell Act IV, in which two daughter cells are produced Assignment: Move tables to sides of room, take 5 minutes to plan the play, dress rehearsal, perform the play.