Sites of Action in Coagulation System Novel Factor Xa and DT Inhibitors

Brief Overview of NOACs

NOACs Important Comparative Features

Effect on NOAC Plasma Levels from D-D Interactions, and Recommendations

Sites of Action in Coagulation System Novel Factor Xa and DT Inhibitors

Brief Overview of NOACs

Ethnic Differences in Rate of ICH

Estimated Levels of Exposure in White and Japanese Patients

Primary Efficacy End Point (Stroke/SEE) mITT Population While on Treatment

Main Safety Results Safety Cohort on Treatment

Lower NOAC Dose Clinical Implications

Incidence of Stroke or Systemic Embolism

Abbreviations

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References

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