Copyright © 2005 American Medical Association. All rights reserved. Younger Gestational Age JAMA. 2005;293(15):1891-1899. doi:10.1001/jama.293.15.1891 Figure Legend: Lipoprotein profiles from cord blood were obtained after sucrose densitygradient ultracentrifugation. The density scale on the x-axis is not a linearscale because it is determined through mathematical transformation of locationsalong the vertical axis of the centrifuge tube (0-35 mm) based on sampledmeasured densities after completion of the spin. The density range used todefine VLDL, LDL, and HDL by this method is given by the width of the bracesunder the x-axes. HDL indicates high-density lipoprotein; LDL, low-densitylipoprotein; and VLDL, very low-density lipoprotein. Date of download: 12/31/2017 Copyright © 2005 American Medical Association. All rights reserved.

Copyright © 2005 American Medical Association. All rights reserved. Younger Gestational Age JAMA. 2005;293(15):1891-1899. doi:10.1001/jama.293.15.1891 Figure Legend: Apo indicates apolipoprotein; MALDI-TOF, matrix-assisted laser desorption/ionizationtime-of-flight; and HDL, high-density lipoprotein. Apo C-I–enrichedHDL (A and B) and normal HDL (C and D) were isolated from plasma of a group0 infant (A and C) and a group 3 infant (B and D) and prepared for MALDI-TOFmass spectrometry (see “Methods” section). Date of download: 12/31/2017 Copyright © 2005 American Medical Association. All rights reserved.

Copyright © 2005 American Medical Association. All rights reserved. Younger Gestational Age JAMA. 2005;293(15):1891-1899. doi:10.1001/jama.293.15.1891 Figure Legend: Plasma lipoproteins were isolated from 4 group 3 infants, 1 group 2infant, and 3 group 0 infants by ultracentrifugation at density greater than1.21 g/mL and prepared for electrophoresis. Following electrophoresis, gelswere stained for protein and densitometric scans performed at 596 nm. Therelative amount of the high-density lipoprotein (HDL) subclasses, using aninternal standard, is depicted on the y-axis. Numbers on the curves indicateHDL particle diameter in nanometers. Date of download: 12/31/2017 Copyright © 2005 American Medical Association. All rights reserved.

Copyright © 2005 American Medical Association. All rights reserved. Younger Gestational Age JAMA. 2005;293(15):1891-1899. doi:10.1001/jama.293.15.1891 Figure Legend: The median and 25th and 75th percentiles (box) and 5th and 95th percentiles(whiskers) for gestational age are shown. The circles represent outliers. Date of download: 12/31/2017 Copyright © 2005 American Medical Association. All rights reserved.

Copyright © 2005 American Medical Association. All rights reserved. Younger Gestational Age JAMA. 2005;293(15):1891-1899. doi:10.1001/jama.293.15.1891 Figure Legend: Plots of gestational age vs large (L3) low-density lipoprotein (LDL)cholesterol and largest (H5) high-density lipoprotein (HDL) cholesterol ingroup 3 (elevated; n = 30) and group 0 (undetectable; n = 27) infants. Regressionlines are depicted for each group. For L3 vs age the regression coefficient r = 0.61 for group 3 infants includes the 1 outlier (28-weekold infant with LDL3 of 73 mg/dL). If the outlier is excluded, the regressioncoefficient (r = 0.52) is still significant.For group 0 infants the regression coefficient was r =0.22. For H5 vs age, the regression coefficients were r = 0.16 for group 3 infants and r = 0.01 forgroup 0 infants. To convert from mg/dL to mmol/L, divide by 38.7. Date of download: 12/31/2017 Copyright © 2005 American Medical Association. All rights reserved.