Clinical Outcome of Chemoradiation Therapy in Patients with Limited-Disease Small Cell Lung Cancer with Ipsilateral Pleural Effusion Seiji Niho, MD,

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Presentation transcript:

Clinical Outcome of Chemoradiation Therapy in Patients with Limited-Disease Small Cell Lung Cancer with Ipsilateral Pleural Effusion Seiji Niho, MD, Kaoru Kubota, MD, Kiyotaka Yoh, MD, Koichi Goto, MD, Hironobu Ohmatsu, MD, Keiji Nihei, MD, Nagahiro Saijo, MD, Yutaka Nishiwaki, MD Journal of Thoracic Oncology Volume 3, Issue 7, Pages 723-727 (July 2008) DOI: 10.1097/JTO.0b013e31817c606a Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Ipsilateral pleural effusion. The arrow indicates the breadth of pleural effusion. Journal of Thoracic Oncology 2008 3, 723-727DOI: (10.1097/JTO.0b013e31817c606a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Breadth of pleural effusion in subgroup A + B, and C. Group A included patients who underwent chemotherapy and thoracic radiotherapy (TRT) (n = 26), group B included patients who did not undergo TRT in spite of the disappearance of pleural effusion after first-line chemotherapy (n = 8), and group C included patients who did not undergo TRT and whose pleural effusion persisted after first-line chemotherapy (n = 28). The line represents the median with the interquartile range. Journal of Thoracic Oncology 2008 3, 723-727DOI: (10.1097/JTO.0b013e31817c606a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 A, Overall survival in the all 699 patients with small cell lung cancer by the proposed seventh edition of the tumor, node, metastasis stage. B, Overall survival in the 649 patients who received chemotherapy as an initial treatment. LD, limited-disease; SCLC, small cell lung cancer; ED, extensive-disease. Journal of Thoracic Oncology 2008 3, 723-727DOI: (10.1097/JTO.0b013e31817c606a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Overall survival in subgroups A, B, and C. Journal of Thoracic Oncology 2008 3, 723-727DOI: (10.1097/JTO.0b013e31817c606a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 5 Overall survival according to the results of cytologic examination for ipsilateral pleural effusion. NE, not examined. Journal of Thoracic Oncology 2008 3, 723-727DOI: (10.1097/JTO.0b013e31817c606a) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions