EEG characteristics & yield in evaluation of first non-febrile seizure in children in Qatar Abdulhafeez M Khair, Khalid Ibrahim, Rana Alshami, Ahmed Veten,

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EEG characteristics & yield in evaluation of first non-febrile seizure in children in Qatar Abdulhafeez M Khair, Khalid Ibrahim, Rana Alshami, Ahmed Veten, Dalal Elmagrabi, Khalid Mohamed Division of Pediatric Neurology, Department of Pediatrics, Hamad Medical Corporation, Doha-Qatar Introduction: Seizures are among the most common neurological disorders in the pediatric age group. Up to 10% of children might experience at least one paroxysmal episode suggestive of seizure activity in their life. It is thought that 5% of all medical attendances to emergency department are related to seizures. Whether the first non-febrile seizure is the kick start of long term epilepsy is always a question that physicians and families encounter. Ordering Electroencephalogram (EEG) for children with first non-febrile seizure is a subject of continuous debate. Objectives: To collect demographic background data for children (1 month to 14 years) who presented with the first non-febrile seizure, To determine the prevalence and pattern of EEG abnormalities in Children (1 month to 14 years) with first non-febrile seizure, and To collect possible evidence sufficient to make a recommendation for the use versus abandoning use of routine EEG in children with first episode of non-febrile seizure.   Methods: In a retrospective single-center observational study around (400) children were admitted with first non-febrile seizure to the Pediatric Emergency Centers (PECs) and their seizure were defined using the international league against epilepsy (ILAE) between January 2013 to December 2014 were studied. EEG was requested for 76 patients. Their EEG were reviewed and interpreted by pediatric neurology consultants. Patients’ demographic data and EEG records are then analyzed. Results: Infants unexpectedly represented a small proportion of our cohort. Male gender predominance was noticed (Figures 1-5).. No significant correlation could be found in EEG yield in regard to seizure type (Table1). Certain patterns of EEG abnormalities were observed (Table2). Conclusions: Epileptic seizure should be diagnosed clinically and EEG is just a helpful tool. Utility of EEG is debatable in childhood first non-febrile seizure. EEG is helpful but interpretation should be individualized. EEG alone is not very good predictors of seizure recurrence or overall prognosis. Larger scale studies with longer follow up are needed. Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Next steps & vision: Prospective recruiting of 2015-2016 patients. Formulation of data base for children with seizures in Qatar. Foundation of epilepsy registry in Qatar. Aiming at 5 years prospective follow up of recruited patients to study data regarding seizure recurrences. Matching seizure recurrence profile with initial EEG recording to evaluate the yield & pridictivity. Finalizing the first evidence-based clinical guidelines in the gulf region for role & utility of EEG in children with 1st non-febrile seizures, at both institutional & national levels. Acknowledgments: Special thanks to all physician & nursing staff members of division of pediatric neurology-HMC. Conflict of interest: None concerning all the authors. Funding: Medical Research Center-HMC,Qatar. Learning points: This is the first epidemiological study in Qatar in regard to children with epilepsy. It has given almost matching results in regard to background factors & yield of diagnosis in this small country with unique population constituents. This study however has formed the first step towards establishing pediatric epilepsy database project in Qatar. Recruiting of more patients & prospective follow up studies are the future visions of this study. Citation: Abdulhafeez MK, et al., J Neurol Neurophysiol 2015, 6:6