IRVING M. REINGOLD, M.D., B.E. KONWALER, M.D. Diseases of the Chest

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Presentation transcript:

Metastatic Malignant Tumors to the Bronchus Found in Bronchial Biopsy and Secretions IRVING M. REINGOLD, M.D., B.E. KONWALER, M.D. Diseases of the Chest Volume 18, Issue 2, Pages 162-170 (August 1950) DOI: 10.1378/chest.18.2.162 Copyright © 1950 The American College of Chest Physicians Terms and Conditions

FIGURE 1, CASE 1 Entire biopsy removed from lumen of right lobe bronchus. Note striking resemblance to adenocarcinoma of the colon from which this is a metastasis. Diseases of the Chest 1950 18, 162-170DOI: (10.1378/chest.18.2.162) Copyright © 1950 The American College of Chest Physicians Terms and Conditions

FIGURE 2, CASE 1 Metastatic adenocarcinoma eroding through bronchus: (A) Adenocarcinoma, (B) Lumen of Bronchus, (C) Respiratory Mucosa of Bronchus, (D) Cartilage. Note marked diminution in size of lumen due to intraluminal projection of the metastasis. Diseases of the Chest 1950 18, 162-170DOI: (10.1378/chest.18.2.162) Copyright © 1950 The American College of Chest Physicians Terms and Conditions

FIGURE 3, CASE 2 Bronchial aspiration in case of metastatic malignant melanoma. Note the large hyperchromatic malignant cells which vary in size and shape. The nuclei of these cells are large and the cytoplasm scant. One tumor cell is pigmented. Diseases of the Chest 1950 18, 162-170DOI: (10.1378/chest.18.2.162) Copyright © 1950 The American College of Chest Physicians Terms and Conditions

FIGURE 4, CASE 3 Polypoid tumor mass extending from peribronchial lymph nodes into main stem bronchus of left lower lobe. The tumor projects through the branches of the bronchus by broad pedicles. Note that the tumor does not encircle the bronchial walls, in contradistinction to cases of stenosing bronchogenic carcinoma. The tumor was a rhabdomyosarcoma, histologically identical with that found in the primary site, the right kidney. Diseases of the Chest 1950 18, 162-170DOI: (10.1378/chest.18.2.162) Copyright © 1950 The American College of Chest Physicians Terms and Conditions