Circulating big endothelin-1: An active role in pulmonary thromboendarterectomy? Frank Langer, MD, Michael Bauer, MD, Dietmar Tscholl, MD, Rene Schramm,

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Presentation transcript:

Circulating big endothelin-1: An active role in pulmonary thromboendarterectomy? Frank Langer, MD, Michael Bauer, MD, Dietmar Tscholl, MD, Rene Schramm, MD, Takashi Kunihara, MD, Henning Lausberg, MD, Thomas Georg, MD, Heinrike Wilkens, MD, Hans-Joachim Schäfers, MD The Journal of Thoracic and Cardiovascular Surgery Volume 130, Issue 5, Pages 1342-1347 (November 2005) DOI: 10.1016/j.jtcvs.2005.06.044 Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Big ET-1 levels during the perioperative course. Preop, Preoperative; postop, postoperative; ARCH, aortic arch replacement. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 1342-1347DOI: (10.1016/j.jtcvs.2005.06.044) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 A, Correlation between preoperative (preop) big ET-1 and preoperative MPAP. B, Correlation between preoperative big ET-1 and MPAP 24 hours after surgery (postop). The Journal of Thoracic and Cardiovascular Surgery 2005 130, 1342-1347DOI: (10.1016/j.jtcvs.2005.06.044) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Receiver operating characteristic curve (AUC, area under the curve) of preoperative big ET-1 level to predict postoperative MPAP. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 1342-1347DOI: (10.1016/j.jtcvs.2005.06.044) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Correlation between peak big ET-1 and maximal vasopressor dosage. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 1342-1347DOI: (10.1016/j.jtcvs.2005.06.044) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions