Hugo J.A. Adams, Rutger A.J. Nievelstein, Thomas C. Kwee  Blood Reviews 

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Opportunities and limitations of bone marrow biopsy and bone marrow FDG-PET in lymphoma  Hugo J.A. Adams, Rutger A.J. Nievelstein, Thomas C. Kwee  Blood Reviews  Volume 29, Issue 6, Pages 417-425 (November 2015) DOI: 10.1016/j.blre.2015.06.003 Copyright © 2015 Elsevier Ltd Terms and Conditions

Fig. 1 A 68-year-old man with extensive FDG-avid bone marrow lesions, demonstrated at coronal maximum intensity projection FDG-PET (A). Blind BMB of the right posterior iliac crest was negative for lymphoma. The large destructive left sacral lesion (A, arrow), also demonstrated at axial CT (B, arrow) and axial FDG-PET/CT (C, arrow), was therefore biopsied using CT guidance (D). Histopathologic examination revealed DLBCL. Blood Reviews 2015 29, 417-425DOI: (10.1016/j.blre.2015.06.003) Copyright © 2015 Elsevier Ltd Terms and Conditions

Fig. 2 Pattern of non-focal, diffusely increased bone marrow FDG uptake (exceeding liver FDG uptake). Blood Reviews 2015 29, 417-425DOI: (10.1016/j.blre.2015.06.003) Copyright © 2015 Elsevier Ltd Terms and Conditions