Alzheimer's & Dementia: The Journal of the Alzheimer's Association FRONTOTEMPORAL DEMENTIA AND PSYCHIATRIC ILLNESS: EMERGING CLINICAL AND BIOLOGICAL LINKS IN GENE CARRIERS Nikolas R. Block, Sharon J. Sha, Anna M. Karydas, Jamie C. Fong, Bruce L. Miller, Howard J. Rosen Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 10, Issue 4, (July 2014) DOI: 10.1016/j.jalz.2014.05.434 Copyright © 2014 Terms and Conditions
Figure 1 Depiction of possible biological changes and corresponding symptomatology. Cases 2 and 3 present psychiatric disease in phase III as an early sign of cell death, whereas cases 5 and 6 present phase-II isolated psychiatric disease and relative recovery during functional synaptic changes and neurotransmitter instability, followed by later phase-III neurodegenerative decline. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2014 10, DOI: (10.1016/j.jalz.2014.05.434) Copyright © 2014 Terms and Conditions