Prognostic Factors in the Treatment of Malignant Pleural Mesothelioma at a Large Tertiary Referral Center Raja M. Flores, MD, Maureen Zakowski, MD, Ennapadam.

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Presentation transcript:

Prognostic Factors in the Treatment of Malignant Pleural Mesothelioma at a Large Tertiary Referral Center Raja M. Flores, MD, Maureen Zakowski, MD, Ennapadam Venkatraman, PhD, Lee Krug, MD, Kenneth Rosenzweig, MD, Joseph Dycoco, BA, Catherine Lee, MD, Cindy Yeoh, MD, Manjit Bains, MD, Valerie Rusch, MD Journal of Thoracic Oncology Volume 2, Issue 10, Pages 957-965 (October 2007) DOI: 10.1097/JTO.0b013e31815608d9 Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Overall survival by histology (p < 0.001). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Survival by pathologic stages I–II versus 3–4 (p < 0.001). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Survival by clinical stages 1–2 versus 3–4 (p < 0.01). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Survival by gender (p < 0.001). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 5 Survival by smoking history (p = 0.002). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 6 Survival by history of asbestos exposure (p < 0.001). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 7 Survival by laterality (p = 0.001). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 8 Survival by symptom presentation (p = 0.02). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 9 Survival by surgical resection, extrapleural pneumonectomy (EPP), and pleurectomy/decortication (P/D) versus ET (exploratory thoracotomy) and nonoperative (p = 0.001). Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 10 Survival by multimodality treatment versus surgical resection alone (p = 0.001). EPP, extrapleural pneumonectomy; P/D, pleurectomy/decortication. Journal of Thoracic Oncology 2007 2, 957-965DOI: (10.1097/JTO.0b013e31815608d9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions