Laboratory features of AL amyloidosis. A

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Laboratory features of AL amyloidosis. A Laboratory features of AL amyloidosis. A. Serum immunofixation electrophoresis reveals an IgGκ monoclonal protein in this example; serum protein electrophoresis is often normal. B. Bone-marrow biopsy sections stained by immunohistochemistry with antibody to CD138 (syndecan, highly expressed on plasma cells) (left) or by in situ hybridization with fluorescein-tagged probes (Ventana Medical Systems) binding to κ mRNA (center) and λ mRNA (right) in plasma cells. (Photomicrograph courtesy of C. O’Hara; with permission.) Source: Amyloidosis, Harrison's Principles of Internal Medicine, 19e Citation: Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J. Harrison's Principles of Internal Medicine, 19e; 2015 Available at: http://accesspharmacy.mhmedical.com/DownloadImage.aspx?image=/data/books/1130/kas_ch137_f003a.png&sec=98711706&BookID=1130&ChapterSecID=79732208&imagename= Accessed: November 07, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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