Combined small cell lung cancer originated from small pure ground-glass nodule— Long-term observation after computed tomography screening Kentaro Miura,

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Combined small cell lung cancer originated from small pure ground-glass nodule— Long-term observation after computed tomography screening Kentaro Miura, Ryoichi Kondo, Makoto Kurai, Junichi Hotta, Toshiro Suzuki, Nobuki Sakaguchi, Muneharu Hayasaka, Keiko Ishii Cancer Treatment and Research Communications Volume 2, Issue 2, Pages 17-20 (January 2014) DOI: 10.1016/j.ctrc.2014.07.001 Copyright © 2014 The Authors Terms and Conditions

Figure 1 Computed tomography (CT) scan. (a) There was a small pure ground-glass nodule (GGN) on the left upper lobe and with a diameter of 12mm and a CT value of −727HU in June 2007. (b) A small solid area (5mm in diameter) appeared with a CT value of +19HU in January 2011. (c) The solid density area had enlarged, and its CT value was +55HU. Cancer Treatment and Research Communications 2014 2, 17-20DOI: (10.1016/j.ctrc.2014.07.001) Copyright © 2014 The Authors Terms and Conditions

Figure 2 Microscopic immuohistochemical findings of the tumor. The adenocarcinoma component contained minimal invasive adenocarcinoma. The tumor was positive for Napsin A at adenocarcinoma component and positive for NCAM (CD56), CgA and SPN at the small cell carcinoma of the lung component. Cancer Treatment and Research Communications 2014 2, 17-20DOI: (10.1016/j.ctrc.2014.07.001) Copyright © 2014 The Authors Terms and Conditions