Sarcoidosis: Treatment with Cortisone, ACTH and Urethane

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Presentation transcript:

Sarcoidosis: Treatment with Cortisone, ACTH and Urethane MICHAEL F. KOSZALKA, M.D., ARTHUR C. FORTNEY, M.D. Diseases of the Chest Volume 23, Issue 4, Pages 444-451 (April 1953) DOI: 10.1378/chest.23.4.444 Copyright © 1953 The American College of Chest Physicians Terms and Conditions

FIGURE 1 Microscopic section (x 150) of a lymph node biopsy made in August 1950, showing nodules of epithelioid cells without necrosis. Diseases of the Chest 1953 23, 444-451DOI: (10.1378/chest.23.4.444) Copyright © 1953 The American College of Chest Physicians Terms and Conditions

FIGURE 2 Roentgenogram of the chest, November 30, 1950, showing cardiac enlargement with marked pulmonary infiltration. Diseases of the Chest 1953 23, 444-451DOI: (10.1378/chest.23.4.444) Copyright © 1953 The American College of Chest Physicians Terms and Conditions

FIGURE 3 Chart summarizing course and therapy during last eight months of illness. Diseases of the Chest 1953 23, 444-451DOI: (10.1378/chest.23.4.444) Copyright © 1953 The American College of Chest Physicians Terms and Conditions

FIGURE 4 Microscopic section (x 60) of lung. Note marked fibrous tissue replacement. Diseases of the Chest 1953 23, 444-451DOI: (10.1378/chest.23.4.444) Copyright © 1953 The American College of Chest Physicians Terms and Conditions

FIGURE 5 Microscopic section (x 100) of lymph node nineteen months after initial biopsy demonstrating fibrous tissue replacement. Note the absence of granulomatosis. Diseases of the Chest 1953 23, 444-451DOI: (10.1378/chest.23.4.444) Copyright © 1953 The American College of Chest Physicians Terms and Conditions