Invest. Ophthalmol. Vis. Sci ;50(11): doi: /iovs Figure Legend:

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Date of download: 6/3/2016 The Association for Research in Vision and Ophthalmology Copyright © All rights reserved. From: Amyloid-β Deposits Lead.

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From: Infection of Human Retinal Pigment Epithelial Cells with Influenza A Viruses Invest. Ophthalmol. Vis. Sci.. 2009;50(11):5419-5425. doi:10.1167/iovs.09-3752 Figure Legend: Influenza A virus replication in retinal pigment epithelial (RPE) cells. (A) Replication kinetics of the influenza virus strains A/New Caledonia/20/99 (H1N1; ●), A/California/7/2004 (H3N2; ▲), or A/Thailand/1(Kan-1)/04 (H5N1; ■) in RPE cells infected with MOI 0.01. (B) Infectious virus titers determined 48 hours p.i. in RPE cells infected with different H5N1 strains at MOI 0.01. (C) Cytopathogenic effects (CPE) and immune staining for influenza A nucleoprotein in RPE cells infected with A/New Caledonia/20/99 (H1N1), A/Thailand/1(Kan-1)/04 (H5N1), or noninfected cells (Mock) 48 hours p.i. (MOI 0.01). Arrowheads: positively stained RPE cells. Arrows: typical dark-pigment granules in the cytoplasm of RPE cells. (D) CPE section in higher magnification to show RPE cell morphology in more detail. Data are the mean ± SD (n = 3). Scale bar, 100 μm. Date of download: 10/31/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.