Utilization of p40 (ΔNp63) with p63 and Cytokeratin 5/6 Immunohistochemistry in Non-Small Cell Lung Carcinoma Fine-Needle Aspiration Biopsy Acta Cytologica.

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Utilization of p40 (ΔNp63) with p63 and Cytokeratin 5/6 Immunohistochemistry in Non-Small Cell Lung Carcinoma Fine-Needle Aspiration Biopsy Acta Cytologica 2013;57:619-624 - DOI:10.1159/000354213 Fig. 1. Composite images from one case demonstrating the various staining patterns of a primary pulmonary SCCA in an EBUS FNA. a Intermediate sized cell group with abundant eosinophilic cytoplasm without clear keratinization. HE stain, cell block. ×40. b p40 shows distinct nuclear labeling of most nuclei within the group. p40 IHC, cell block. ×60. c p63 shows distinct nuclear labeling of most nuclei within the group. p63 IHC, cell block. ×60. d CK5/6 shows strong cytoplasmic staining with negative images of the nuclei. CK5/6 IHC, cell block. ×60. © 2013 S. Karger AG, Basel