Genetic Research Using Bioinformatics: LESSON 5:

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Presentation transcript:

Genetic Research Using Bioinformatics: LESSON 5: Protein Structure and Function: A Molecular Murder Mystery PowerPoint slides to accompany Using Bioinformatics: Genetic Research

Molecular Diagnostics Researcher James Ferrenberg Place of Employment: University of Washington Molecular Diagnostics Lab Virology Division Type of Work: Develop tests to diagnose different types of viral infections Discovery is really exciting and there is nothing cooler (in my job) than designing an assay and finding it works great and generates important data.

Mitochondria: The Powerhouse of the Cell Present in almost all cells. Inner membrane contains the electron transport chain. Metabolizes sugar and fats into ATP. Mitochondrial DNA (mtDNA). Source: Wikimedia Commons.

Food (Sugar and Fats) Go In ATP Comes Out Source: Roxxychan, Wikimedia Commons.

3D Structure of the Cytochrome c Oxidase Complex Intermembrane Space Inner Mitochondrial Membrane Matrix Source: Tsukihara et al. 1996. Science 272:1136.

Molecular Diagnostics Researcher James Ferrenberg Place of Employment: University of Washington Molecular Diagnostics Lab Virology Division Type of Work: Develop tests to diagnose different types of viral infections Discovery is really exciting and there is nothing cooler (in my job) than designing an assay and finding it works great and generates important data.

CAREERS IN SPOTLIGHT: Molecular Diagnostics Researcher What do they do? Develop tests and methods to identify a disease or the predisposition to a disease by analyzing the DNA or RNA of an infectious organism (virus, bacteria, or parasite). What kind of training is involved? Associate’s degree and/or Bachelor’s degree What is a typical salary for a Molecular Diagnostics Researcher? Starting: $35,000-$45,000/year ($17.50-$22.00/hour) Up to: $55,000-$65,000/year ($26.00-$31.00/hour) Source: Genome Technology Salary Survey 2010