Christian S. Meyhoff, MD, PhD

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Presentation transcript:

Oxygen fraction during surgery - should we use high FiO2 to prevent surgical site infection? Christian S. Meyhoff, MD, PhD Department of Anaesthesia and Intensive Care Bispebjerg and Frederiksberg Hospital, University of Copenhagen christian.sahlholt.meyhoff@regionh.dk

Wetterslev et al. Cochrane Database Syst Review 2015 christian.sahlholt.meyhoff@regionh.dk

Risk of hypercapnia: SpO2 88-92% Routine: SpO2 94-98% Risk of hypercapnia: SpO2 88-92% christian.sahlholt.meyhoff@regionh.dk

Supranormal perioperative oxygen treatment No large benefit for wound healing Potential excess mortality Potential affection of cancer recurrence Potential cardiac and cerebral side effects Requires further evaluation in high-risk patients; your collaboration highly appreciated! christian.sahlholt.meyhoff@regionh.dk

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