The Pattern of Use of Hypofractionated Radiation Therapy for Early-Stage Breast Cancer in New South Wales, Australia, 2008 to 2012 Geoff P. Delaney,

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The Pattern of Use of Hypofractionated Radiation Therapy for Early-Stage Breast Cancer in New South Wales, Australia, 2008 to 2012 Geoff P. Delaney, MBBS (Hons), FRANZCR, MD, PhD, Senthilkumar Gandhidasan, MBBS, MPH, MHI, FRANZCR, Richard Walton, MSc, Frances Terlich, BMathFin, MStat, Deborah Baker, BAppSc, Grad Dipl Appl Epi, MPH, David Currow, BMed, MPH, PhD, FRACP International Journal of Radiation Oncology • Biology • Physics Volume 96, Issue 2, Pages 266-272 (October 2016) DOI: 10.1016/j.ijrobp.2016.05.016 Copyright © 2016 Terms and Conditions

Fig. 1 Variations in fractionation regimen and median age by fractionation type by facility of treatment. Lighter shade: standard fractionation. Darker shade: hypofractionation use. International Journal of Radiation Oncology • Biology • Physics 2016 96, 266-272DOI: (10.1016/j.ijrobp.2016.05.016) Copyright © 2016 Terms and Conditions

Fig. 2 (A) Increase in uptake of hypofractionation in New South Wales over time (though not reflected in all facilities). (B) Association of increasing age with increasing use of hypofractionation in all facilities but with marked variation in baseline rates. (C, D) Increase in hypofractionation over time, showing relatively more increase in the right breast, as expected to be evident primarily in facilities with a lower use of hypofractionation. International Journal of Radiation Oncology • Biology • Physics 2016 96, 266-272DOI: (10.1016/j.ijrobp.2016.05.016) Copyright © 2016 Terms and Conditions