From: Inhibition of Apoptosis and Reduction of Intracellular pH Decrease in Retinal Neural Cell Cultures by a Blocker of Carbonic Anhydrase Invest. Ophthalmol. Vis. Sci.. 2006;47(3):1185-1192. doi:10.1167/iovs.05-0555 Figure Legend: Inhibition of glyoxal- and hydrogen peroxide–induced apoptosis by dorzolamide. (A) Cells were incubated with 0.3 mM glyoxal (dark bar) or with 0.3 mM glyoxal together with 0.3 mM dorzolamide (light bar) for 24 hours. (B) Incubation with 0.3 mM hydrogen peroxide (in HBSS, as described in the legend to Fig. 2 ) for 30 minutes without (dark bar) or with (light bar) 0.3 mM dorzolamide. After 30 minutes, the HBSS containing hydrogen peroxide was exchanged for medium. Data represent the mean ± SEM of four (dark bars) or three (light bars) independent experiments. Date of download: 10/16/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.