Clinical Transplantation of Initially Rejected Donor Lungs After Reconditioning Ex Vivo Richard Ingemansson, MD, PhD, Atli Eyjolfsson, MD, Lena Mared,

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Clinical Transplantation of Initially Rejected Donor Lungs After Reconditioning Ex Vivo Richard Ingemansson, MD, PhD, Atli Eyjolfsson, MD, Lena Mared, MD, Leif Pierre, CCP, BSc, Lars Algotsson, MD, PhD, Björn Ekmehag, MD, PhD, Ronny Gustafsson, MD, PhD, Per Johnsson, MD, PhD, Bansi Koul, MD, PhD, Sandra Lindstedt, MD, PhD, Carsten Lührs, MD, Trygve Sjöberg, PhD, Stig Steen, MD, PhD The Annals of Thoracic Surgery Volume 87, Issue 1, Pages 255-260 (January 2009) DOI: 10.1016/j.athoracsur.2008.09.049 Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Schematic drawing of the ex vivo lung reconditioning system. The lungs are placed in the reconditioning box, connected to the perfusion system and a ventilator. The cannulation is done through a piece of aorta (A), harvested from the donor, and used to prolong the pulmonary artery. The blood coming out from the remaining dorsal part of the left atrium (LA) runs freely out in the box. Pulmonary arterial pressure (PAP) is measured continuously. Blood gases are measured in the blood before and after the lung. The shunt with the tube clamp is used to prime the system with STEEN Solution mixed with erythrocytes to a hematocrit of 10% to 15%. The Annals of Thoracic Surgery 2009 87, 255-260DOI: (10.1016/j.athoracsur.2008.09.049) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions