Atopy and Development of Cancer: A Population-Based Prospective Study

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Presentation transcript:

Atopy and Development of Cancer: A Population-Based Prospective Study Tea Skaaby, MD, Lise Lotte Nystrup Husemoen, PhD, Nina Roswall, PhD, Betina Heinsbaek Thuesen, PhD, Allan Linneberg, PhD The Journal of Allergy and Clinical Immunology: In Practice Volume 2, Issue 6, Pages 779-785.e15 (November 2014) DOI: 10.1016/j.jaip.2014.06.010 Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 1 Meta-estimates of the study-specific estimates from fixed effect models of the association between being individuals with atopy compared with individuals without atopy and the risk of cancer. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E1 Flowchart of the 1936-cohort. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E2 Flowchart of the Monica1 study. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E3 Flowchart of the Allergy98 study. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E4 Flowchart of the Inter99 study. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E5 Flowchart of the Health2006 study. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E6 Meta-analysis of the study-specific estimates of the association between atopy and non-melanoma skin cancer (NMSC). Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval; NMSC, non-melanoma skin cancer. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E7 Meta-analysis of the study-specific estimates of the association between atopy and cancer of the urinary organs. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E8 Meta-analysis of the study-specific estimates of the association between atopy and total cancer excluding non-melanoma skin cancer (NMSC). Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval; NMSC, non-melanoma skin cancer. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E9 Meta-analysis of the study-specific estimates of the association between atopy and prostate cancer. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E10 Meta-analysis of the study-specific estimates of the association between atopy and cancer of the bronchus and lung. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E11 Meta-analysis of the study-specific estimates of the association between atopy and malignant melanoma. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E12 Meta-analysis of the study-specific estimates of the association between atopy and head and neck cancer. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E13 Meta-analysis of the study-specific estimates of the association between atopy and colorectal cancer. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E14 Meta-analysis of the study-specific estimates of the association between atopy and cancer. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E15 Meta-analysis of the study-specific estimates of the association between atopy and breast cancer. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure E16 Meta-analysis of the study-specific estimates of the association between atopy and cancer of the uterus. Abbreviations: A98, Allergy98; C36, 1936-cohort; H06, Health2006; I99, Inter99; M1, Monica1; CI, confidence interval. The Journal of Allergy and Clinical Immunology: In Practice 2014 2, 779-785.e15DOI: (10.1016/j.jaip.2014.06.010) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions