RENAL DRUGS Henderson

Composed of the kidneys and represents a major route to eliminate drugs. Produces and regulates body fluid and electrolyte balance Renal System

A disease characterized by overproduction or insufficient elimination of uric acid within the body that will crystalize in the joints and cause pain/inflammation Gout

Salts which are dissolved in body fluids and are necessary in proper concentration to maintain normal body functions Ammonium Bicarbonate Calcium Chloride Magnesium Phosphate Potassium Sodium Electrolytes

Alter the body’s electrolyte pattern by prohibiting or enhancing excretion of electrolytes. Uses: Hypertension (high blood pressure) CHF Fluid Retention SPECIAL NOTE: Most diuretics deplete potassium, frequently, potassium is prescribed along with a diuretic. Diuretics

Thiazide and related diuretics Causes the kidney to secrete more which decreases water retention and blood pressure. Used to reduce blood pressure Side effects: Increased urination, weakness, upset stomach, dizziness Brand Generic Hydrodiuril Hydrochlorothiazide Lozol Indapamide Thiazide and related diuretics

Loop diuretics Very potent diuretic Used to treat CHF Brand Generic Bumex Bumetanide Lasix Furosemide Demadex Torsemide Loop diuretics

Potassium Sparing diuretics These are weak diuretics and typically are prescribed in addition to another diuretic to treat CHF. No potassium supplement required Brand Generic Aldactone Spironolactone Potassium Sparing diuretics

Combination diuretics Brand Generic Moduretic Amiloride/HCTZ Maxide/Diazide Triamterene/HCTZ Aldactazide Spironolactone/HCTZ Combination diuretics

Pull water out of the body and into the kidneys to produce an intense diuresis in a hospital setting. Example: Mannitol Osmotic Diuretics

Enhance excretion of uric acid for the prevention and treatment of gout. Side effects: Rash, kidney stones Brand Generic Zyloprim Allopurinol Benamid Probenacid Colcrys Colchicine Gout treatment