Different pathways to Alzheimer’s disease Different pathways to Alzheimer’s disease? atrophy, hypometabolism, and beta-amyloid deposition in diagnostic groups at increased risk Miranka Wirth, Alexandre Bejanin, Eider M. Arenaza-Urquijo, Julie Gonneaud, Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Florence Mézenge, Vincent de La Sayette, Béatrice Desgranges, Gaël Chételat Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 7, Pages P2-P3 (July 2015) DOI: 10.1016/j.jalz.2015.06.004 Copyright © 2015 Terms and Conditions
Figure 1 Voxel-wise intra-modality comparisons between regional degrees of atrophy, hypermetabolism and amyloid deposition in diagnostic groups with 1A. Mild Cognitive Impairment (MCI), 1B. Subjective Memory Decline (SCD), 1C. CN APOE4 carriers as well as 0. AD patients (for visual comparison). Contrast maps were displayed on the left hemisphere thresholded at t -values of p < 0.001 uncorrected, k = 20. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2015 11, P2-P3DOI: (10.1016/j.jalz.2015.06.004) Copyright © 2015 Terms and Conditions