From: Glycogene Expression in Conjunctiva of Patients with Dry Eye: Downregulation of Notch Signaling Invest. Ophthalmol. Vis. Sci.. 2009;50(6):2666-2672.

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From: Glycogene Expression in Conjunctiva of Patients with Dry Eye: Downregulation of Notch Signaling Invest. Ophthalmol. Vis. Sci.. 2009;50(6):2666-2672. doi:10.1167/iovs.08-2734 Figure Legend: Real-time PCR analysis of Notch1, Notch3, and Jagged1. (A) By real-time PCR, Notch1, Notch3, and their ligand, Jagged1, were significantly downregulated in the conjunctiva of patients with dry eye (P < 0.05). (B) Comparison of microarray and real-time PCR showed downward trends in the results, with real-time PCR analyses resulting in more pronounced differences in expression of Notch signaling genes between normal subjects and patients with dry eye. (C) Conventional PCR after 30 cycles of cDNA amplification produced a unique band corresponding to the predicted size for Notch1 (75 bp), Notch3 (105 bp), and Jagged1 (76 bp). Date of download: 10/8/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.