BDNF: brain-derived neurotrophic factor CRP: C-reactive protein

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Presentation transcript:

A SELECTED LIST OF ADIPOSE-DERIVED MEDIATORS, AS RELATED TO CARDIOMETABOLIC RISK BDNF: brain-derived neurotrophic factor CRP: C-reactive protein IL: interleukin MIP-1 (CCL2): monocyte chemoattractant protein MIP-1 (Cysteine-Cysteine motif chemokine ligand 2) NGF: nerve growth factor PAI-1: plasminogen activator inhibitor-1 RANTES: regulated on activated normal T-cell expressed and secreted TNF-α: tumour necrosis factor-α Note: all components of renin-angiotensin system are expressed in perivascular adipose tissue, suggesting their paracrine involvement in cardiovascular disease. Adapted from Chaldakov G. J Exp Clin Res 2008; 9: 81-8