Volume 370, Issue 9586, Pages (August 2007)

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Volume 370, Issue 9586, Pages 493-503 (August 2007) Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial Dr Jonathan Mant, MD, Prof FD Richard Hobbs, FMedSci, Kate Fletcher, BA, Andrea Roalfe, MSc, Prof David Fitzmaurice, MD, Prof Gregory YH Lip, MD, Ellen Murray, PhD The Lancet Volume 370, Issue 9586, Pages 493-503 (August 2007) DOI: 10.1016/S0140-6736(07)61233-1 Copyright © 2007 Elsevier Ltd Terms and Conditions

Figure 1 Trial profile AF=atrial fibrillation. The Lancet 2007 370, 493-503DOI: (10.1016/S0140-6736(07)61233-1) Copyright © 2007 Elsevier Ltd Terms and Conditions

Figure 2 Kaplan-Meier plot of adherence to allocated treatment The Lancet 2007 370, 493-503DOI: (10.1016/S0140-6736(07)61233-1) Copyright © 2007 Elsevier Ltd Terms and Conditions

Figure 3 Kaplan-Meier plot of time to primary event The Lancet 2007 370, 493-503DOI: (10.1016/S0140-6736(07)61233-1) Copyright © 2007 Elsevier Ltd Terms and Conditions

Figure 4 Relative risk of all primary events by subgroup Bars show the 95% CIs calculated by Poisson exact method. The broken line shows relative risk of primary events in the whole trial population. TIA=transient ischaemic attack. The Lancet 2007 370, 493-503DOI: (10.1016/S0140-6736(07)61233-1) Copyright © 2007 Elsevier Ltd Terms and Conditions

Figure 5 Indirect comparison of results from BAFTA for ischaemic stroke and major haemorrhage with results from six other randomised trials of aspirin versus anticoagulation BAFTA results are compared with those from a meta-analysis by Van Walraven and colleagues8 that used data from individual patients aged ≥75 years from six previous studies. The Lancet 2007 370, 493-503DOI: (10.1016/S0140-6736(07)61233-1) Copyright © 2007 Elsevier Ltd Terms and Conditions