ALK-positive plasmablastic B-cell lymphoma with expression of the NPM-ALK fusion transcript: report of 2 cases by Mihaela Onciu, Frederick G. Behm, James.

Slides:



Advertisements
Similar presentations
Diffuse large B-cell lymphoma: reduced CD20 expression is associated with an inferior survival by Nathalie A. Johnson, Merrill Boyle, Ali Bashashati, Stephen.
Advertisements

Lymphoma dissemination: the other face of lymphocyte homing by Steven T. Pals, David J. J. de Gorter, and Marcel Spaargaren Blood Volume 110(9):
Hydroa vacciniforme-like lymphoma: a chronic EBV + lymphoproliferative disorder with risk to develop a systemic lymphoma by Leticia Quintanilla-Martinez,
A novel anti-CD37 antibody-drug conjugate with multiple anti-tumor mechanisms for the treatment of B-cell malignancies by Jutta Deckert, Peter U. Park,
CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms.
Reduced-intensity allogeneic transplantation in pediatric patients ineligible for myeloablative therapy: results of the Pediatric Blood and Marrow Transplant.
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications by Elias Campo, Steven H. Swerdlow, Nancy L.
CD11b is a therapy resistance– and minimal residual disease–specific marker in precursor B-cell acute lymphoblastic leukemia by Peter Rhein, Rita Mitlohner,
Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases by Porcia T. Bradford, Susan S. Devesa, William F. Anderson,
Rac GTPases play critical roles in early T-cell development by Celine Dumont, Agnieszka Corsoni-Tadrzak, Sandra Ruf, Jasper de Boer, Adam Williams, Martin.
Epratuzumab with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy in patients with previously untreated diffuse large.
EBV-positive diffuse large B-cell lymphoma of the elderly by Chi Young Ok, Thomas G. Papathomas, L. Jeffrey Medeiros, and Ken H. Young Blood Volume 122(3):
Generating AML-Specific Peripheral Blood Autologous Cytotoxic T-Lymphocytes (CTLs)‏ by Rohtesh S. Mehta, Xiaohua Chen, Antony Jeyaraj, and Paul Szabolcs.
Formation of human hepatocytes by human hematopoietic stem cells in sheep by Graça Almeida-Porada, Christopher D. Porada, Jason Chamberlain, Ali Torabi,
A phase I/II trial of iodine-131–tositumomab (anti-CD20), etoposide, cyclophosphamide, and autologous stem cell transplantation for relapsed B-cell lymphomas.
Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B- cell lymphomas by Lingchen Fu, Yen-Chiu Lin-Lee,
Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells by Jonathan M. Irish,
The influence of high-altitude living on body iron
Do HSCs divide asymmetrically?
Comparable results of umbilical cord blood and HLA-matched sibling donor hematopoietic stem cell transplantation after reduced-intensity preparative regimen.
by Dai Chida, Osamu Miura, Akihiko Yoshimura, and Atsushi Miyajima
TCR-MHC-peptide(s): in vivo veritas
“Vitamin hypothesis”: explanation for allergy increase?
Platelet Antibody Testing in Idiopathic Thrombocytopenic Purpura
Finding a diamond in the (mouse is) rough
by Udomsak Bunworasate, Hilal Arnouk, Hans Minderman, Kieran L
by James O. Armitage, and Dan L. Longo
Deregulated expression of the Myc cellular oncogene drives development of mouse “Burkitt-like” lymphomas from naive B cells by Delin Zhu, Chen Feng Qi,
A Clinical Evaluation of the International Lymphoma Study Group Classification of Non-Hodgkin's Lymphoma Blood Volume 89(11): June 1, 1997 ©1997.
Nonmyeloablative conditioning for relapsed follicular lymphoma
Inhibition of ILK restores epithelial ZO-1 and E-cadherin and inhibits fibronectin and Snail1 expression after TGF-β1 treatment. Inhibition of ILK restores.
by Petri Salven, Lasse Teerenhovi, and Heikki Joensuu
Allogeneic Bone Marrow Transplantation for Low-Grade Lymphoma
SOX11 holds mantle cell lymphoma’s key to home
Fusion genes in cord blood
An Unusual Cause of Abdominal Pain in Sickle Cell Disease
What is a true ALCL? by Wolfram Klapper Blood Volume 124(9):
Treating limited-stage nodular lymphocyte predominant Hodgkin lymphoma similarly to classical Hodgkin lymphoma with ABVD may improve outcome by Kerry J.
Telomerase regulation in HTLV-I infection
Relationship of p53, bcl-2, and Tumor Proliferation to Clinical Drug Resistance in Non-Hodgkin's Lymphomas by Wyndham H. Wilson, Julie Teruya-Feldstein,
AIDS-Related Extranodal Non-Hodgkin's Lymphomas With Plasma Cell Differentiation by Antonino Carbone, Annunziata Gloghini, Vincenzo Canzonieri, Umberto.
Gene expression profiling of pediatric acute myelogenous leukemia
Basophils take a slice of IRF8 pie
by Douglas D. Ross, Judith E. Karp, Tar T. Chen, and L. Austin Doyle
Hepatitis C infection among survivors of childhood cancer
Primary testicular lymphoma
Upfront double high-dose chemotherapy with DICEP followed by BEAM and autologous stem cell transplantation for poor-prognosis aggressive non-Hodgkin lymphoma.
Latest lymphoma classification is skin deep
Improvements in observed and relative survival in follicular grade 1-2 lymphoma during 4 decades: the Stanford University experience by Daryl Tan, Sandra.
Lymphoma spread? Target CD47-SIRPα!
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains anIGH/MMSET fusion transcript by Madhumita.
HU for acute treatment of sickle VOC?
How I treat refractory CLL
by George Z. Rassidakis, Mauricio P. Oyarzo, and L. Jeffrey Medeiros
Anergy: the CLL cell limbo
Acute mixed lineage leukemia in children: the experience of St Jude Children's Research Hospital by Jeffrey E. Rubnitz, Mihaela Onciu, Stanley Pounds,
by John J. Strouse, Megan E. Reller, David G
Cytokine-Release Syndrome in Patients With B-Cell Chronic Lymphocytic Leukemia and High Lymphocyte Counts After Treatment With an Anti-CD20 Monoclonal.
by Martin S. Tallman, Donna Neuberg, John M. Bennett, Christopher J
by Wendy Lim, Sara K. Vesely, and James N. George
Erratum in Ledru et al. Alteration of tumor necrosis factor–α T-cell homeostasis following potent antiretroviral therapy: contribution to the development.
Thrombotic thrombocytopenic purpura: diagnostic criteria, clinical features, and long-term outcomes from 1995 through 2015 by Evaren E. Page, Johanna A.
Resistance mechanism for ibrutinib in marginal zone lymphoma
Rituximab immunotherapy: it’s getting personal
Mesenchymal Stem Cell-Derived Vesicles Reverse Hematopoietic Radiation Damage by Sicheng Wen, Laura R Goldberg, Mark S Dooner, John L Reagan, and Peter.
Hepatosplenic T-Cell Lymphoma: Clinicopathological Features and Treatment Outcomes: Report From The North American Peripheral T-Cell Lymphoma Consortium.
Patient Tregs express normal levels of suppression.
by Victor A. Chow, Mazyar Shadman, and Ajay K. Gopal
Cold agglutinin disease
Outcomes in patients with PTCL
Presentation transcript:

ALK-positive plasmablastic B-cell lymphoma with expression of the NPM-ALK fusion transcript: report of 2 cases by Mihaela Onciu, Frederick G. Behm, James R. Downing, Sheila A. Shurtleff, Susana C. Raimondi, Zhigui Ma, Stephan W. Morris, Wren Kennedy, Sandra C. Jones, and John T. Sandlund Blood Volume 102(7): October 1, 2003 ©2003 by American Society of Hematology

Morphologic and immunophenotypic features of ALK-positive large B-cell lymphoma. Mihaela Onciu et al. Blood 2003;102: ©2003 by American Society of Hematology

RT-PCR analysis demonstrating the presence of the NPM-ALK fusion transcript and the absence of mRNA for the extracellular portion of ALK in 2 cases of ALK-positive B-cell lymphoma. Mihaela Onciu et al. Blood 2003;102: ©2003 by American Society of Hematology