Defective B-cell memory in patients with Down syndrome Ruud H.J. Verstegen, MD, Gertjan J. Driessen, MD, Sophinus J.W. Bartol, BSc, Carel J.M. van Noesel,

Slides:



Advertisements
Similar presentations
Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,
Advertisements

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,
Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,
Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.
Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: A double-blind randomized controlled trial Saifudin.
Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor κB activation So Ri Kim, MD, PhD, Dong Im Kim, MS, Mi.
Isaac J. Nijman, PhD, Joris M
D-dimer: A biomarker for antihistamine-resistant chronic urticaria
Predictors of new fragility fractures after diagnosis of indolent systemic mastocytosis  Eveline van der Veer, PhD, Suzanne Arends, PhD, Sjoukje van der.
Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 
Risk of an asthma exacerbation after bariatric surgery in adults
Clarification concerning amoxicillin skin testing
Quoting a landmark paper on the beneficial effects of probiotics
Fatty acids, inflammation, and asthma
Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 
Human CD19 and CD40L deficiencies impair antibody selection and differentially affect somatic hypermutation  Menno C. van Zelm, PhD, Sophinus J.W. Bartol,
Dennis K. Ledford, MD, Sally Wenzel, MD 
Is 9 more than 2 also in allergic airway inflammation?
Desensitization to Chemotherapeutic Agents
Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD 
Fatty acids, inflammation, and asthma
Heleen D. de Koning, MD, Joost Schalkwijk, PhD, Jos W. M
Association between (CCTTT)n repeat polymorphism in NOS2 promoter and asthma exacerbations  Keita Hirai, PhD, Toshihiro Shirai, MD, PhD, Masayuki Suzuki,
Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J
Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis  George Philip, MD, Janet van Adelsberg, MD, Thomas Loeys, PhD, Nancy.
Physician needs in health informatics: Just ask the docs
Peter M. Wolfgram, MD, David B. Allen, MD 
William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P
Defective B-cell memory in patients with Down syndrome
René van Gent, MD, Cornelis K. van der Ent, MD, PhD, Maroeska M
Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA 
Reply Journal of Allergy and Clinical Immunology
Debra J. Palmer, PhD, Thomas R. Sullivan, BMa&CompSc(Hons), Michael S
Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation  Leif Bjermer, MD  Journal of Allergy.
What are the best outcome measurements for atopic eczema
Predictors of new fragility fractures after diagnosis of indolent systemic mastocytosis  Eveline van der Veer, PhD, Suzanne Arends, PhD, Sjoukje van der.
Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management  Scott H. Sicherer, MD, Hugh A. Sampson, MD  Journal.
Biosimilars and drug development in allergic and immunologic diseases
Christian Hennig, MD, Christine Happle, MD, Gesine Hansen, MD 
Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A
A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity  Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,
What is an “eosinophilic phenotype” of asthma?
Cephalosporin Side Chain Cross-reactivity
H. William Kelly, PharmD  Journal of Allergy and Clinical Immunology 
Autophagy: Nobel Prize 2016 and allergy and asthma research
Higher incidence of pediatric anaphylaxis in northern areas of the United States  William J. Sheehan, MD, Dionne Graham, PhD, Lin Ma, MS, Sachin Baxi,
Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment
Advances in the approach to the patient with food allergy
Impact of Down syndrome on the performance of neonatal screening assays for severe primary immunodeficiency diseases  Ruud H.J. Verstegen, MD, Stephan.
Geographic variability in childhood asthma prevalence in Chicago
New pathways for itching in patients with atopic dermatitis?
One step forward, 2 steps back: The enigma of preschool wheeze
Benjamin Chaigne, MD, Hervé Watier, MD, PhD 
Acid-suppressive drug use in pregnancy and the toddler's asthma risk: A crossover, case-control study  Bianca Mulder, BSc, Catharina Carolina Maria Schuiling-Veninga,
Measles and immunomodulation
Guus A. Westerhof, MD, Elise M. Vollema, MD, Els J
The Editors' Choice Journal of Allergy and Clinical Immunology
Macrolide antibiotics and asthma treatment
Asthma: The past, future, environment, and costs
Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity  Gertjan.
Dendritic cells in nasal mucosa of subjects with different allergic sensitizations  Susanne M. Reinartz, MD, Joost van Tongeren, MD, Danielle van Egmond,
Environmental factors and eosinophilic esophagitis
The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy  Jennifer M. Maloney, MD, Magnus Rudengren, BSc, Staffan.
Advances in pediatric asthma in 2007
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Safety and efficacy of repeated monthly carboplatin desensitization
Natural history of cow’s milk allergy
Primary prevention of asthma and allergy
Itching as a systemic disease
Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity  Gertjan.
Presentation transcript:

Defective B-cell memory in patients with Down syndrome Ruud H.J. Verstegen, MD, Gertjan J. Driessen, MD, Sophinus J.W. Bartol, BSc, Carel J.M. van Noesel, MD, PhD, Louis Boon, PhD, Mirjam van der Burg, PhD, Jacques J.M. van Dongen, MD, PhD, Esther de Vries, MD, PhD, Menno C. van Zelm, PhD Journal of Allergy and Clinical Immunology Volume 134, Issue 6, Pages e9 (December 2014) DOI: /j.jaci Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig 1 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig 2 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig 3 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig 4 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig E1 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig E2 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig E3 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions

Fig E4 Journal of Allergy and Clinical Immunology , e9DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions Terms and Conditions