Liquid Medication Delivery System Engineering World Health Amanda Feest – Team Leader Val Maharaj – BSAC Nate Cira – Communicator Brian Mogen – BWIG Prof. Thompson – Advisor Prof. Webster – UW contact Prof. Malkin – EWH contact

Outline Problem Statement Background Product Design Specifications Design Alternatives Decision Matrix Future work

Problem Statement Seal donated medication bottles Measure the proper dosage Dispense medication Must be inexpensive

Background Current Donation Program Goal: To effectively distribute donated medication Viramune® (NNRTI) donated by Boehringer Ingelheim Reduces mother-to-child transmission by 50% 3 2

Background Current dispensing method Method Syringe inserted into bottle Dose drawn up Syringe capped, put in foil pouch Problems Expensive Can spill while dispensing Open to air (spoilage/contamination) Must have multiple parts present

Product Design Specifications Must dispense at least 4000 doses Must be produced in quantities of 2000 Must be manufactured for $2/device Goal of 50¢/device Must dispense.6mL ±.05mL Materials must not react with medication

Advantages Cheap Easy to manufacture Low maintenance Disadvantages Low accuracy May not be applicable for all bottle types Positive Pressure Device

“Liquid Pour” Spout Advantages Very easy to use Can be formatted for all bottle types Disadvantages Expensive Hard to manufacture Low accuracy One dose always exposed 4

Stopper and Syringe Sealed with a stopper Tubing attaches components Syringe withdraws and expels dosage

T Valve Rotating T valve Champagne rubber stopper Syringe Tubing 9

One Way Valves T junction One way valves Champagne rubber stopper Syringe Tubing

Valve Types Ball check valve Binder Clip 1011

Perforated Tube Perforated tube Champagne rubber stopper Syringe One way valve

Positive pressure device Liquid Pour Spout Syringe and tubing Ability to meet cost target (20%) Accuracy of dose (20%) Sterility (20%)10616 Ease of manufacture (10%) 7310 Ease of assembly (10%) 7107 Ease of use (10%)10 8 Durability (10%)1098 Total Design Matrix

Future Work Submit design to EWH Order supplies Build prototype Test prototype Enter the EWH competition

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