Welcome to N 152
Diffusion The tendency of a molecule to move from a region of high concentration to one of lower concentration. Can be altered by: –The partial pressure gradient of the gases –The thickness of the respiratory membrane –Pressure in the pulmonary circulation –Surface area available
Perfusion The flow of blood that supplies tissues and cells with needed nutrients and oxygen
Chemoreceptor control of respirations Groups of nerve cells that can distinguish between hydrogen ions and oxygen Exert greatest influence on the autonomic nervous system’s control of ventilation by correlating acid-base balance with gas exchange requirements Located both centrally and peripherally (carotid arteries and arch of the aorta)
Anterior Landmarks
Posterior Landmarks
Lateral Landmarks
History HPI –Current symptoms –Chief complaint Dyspnea Cough Sputum production Hemoptysis Wheezing, stridor Chest pain Cyanosis
Ability to Breath Respiratory Rate Minute ventilation Vital capacity Inspiratory force
Chest Diameter
Chest Abnormalities
Percussion Notes Resonance Hyperresonance Dull Flat Tympany
Normal Breath Sounds
Adventitious Breath Sounds Crackles Rhonchi Wheezes Pleural Friction Rub
Normal V/Q
Low V/Q
High V/Q
Silent Unit
Lung Volume Tests Tidal Volume (V T ) –The volume of air inspired and expired during the respiratory cycle. 5-8 ml/kg Inspiratory Reserve Volume (IRV) –The maximal amount of air that can be inspired after a normal inspiration Expiratory Reserve Volume (ERV) –The maximal amount of air that can be expired after a normal inspiration Residual Volume (RV) –The volume of air remaining in the lungs at the end of maximum expiration
Peak Flow Meters
Lung Capacity Tests Functional Residual Capacity (FRC) –The volume of air remaining in the lungs at the end of normal expiration. Calculated measurement of of airway resistance. Vital Capacity (VC) –The maximum amount of air that can be expired slowly and completely after a maximum inspiration Total Lung Capacity (TLC) –The volume of air contained in the lung after maximal inspiration
Pulmonary Spirometry Tests Forced Vital Capacity (FVC) –The volume of air expired forcefully and rapidly after maximal inspiration –Measured over over a specific interval of time Peak Expiratory Flow Rate (PEFR) –The maximum flow rate attainable at the beginning of forced expiration
Obstructive Disorders Increased resistance to airflow –Emphysema, asthma, chronic bronchitis, bronchiectasis VC TLC FRC RV FEV1
Restrictive Disorders Compliance of lungs, chest wall, or both –Neuromuscular diseases: polio, MD, kyphoscoliosis, chest wall abnormalities VC TLC Normal FRC Normal RV FEV1
Arterial Blood Gases pH:7.35 – 7.45 PCO 2 :35 – 45 mm Hg HCO 3 :22-26 mEq
General Imbalances Acidosis:< 7.35 –An accumulation of either acids or a loss of bicarbonate Alkalosis:> 7.45 –An accumulation of base or a loss of acids
Respiratory Acidosis Etiology: hypoventilation Causes: pain, drugs, neuromuscular disorders, obstructive/restrictive lung diseases, respiratory center depression, fatigue, mechanical hypoventilation Sx: decreased mental status, drowsiness, restlessness, tachycardia, hypoventilation, headache, weakness, tremors
Respiratory Acidosis (cont) Non Invasive Treatment –Voluntary deep breathing –IPPB –Incentive devices –Pain medication Invasive Treatment –Artificial airway –Mechanical ventilation
Respiratory Alkalosis Etiology: hyperventilation Causes: anxiety, fear, pain, fever, sepsis, brain lesion, hypoxia, exercise, mechanical hyperventilation Sx: increased respiratory rate, increased tidal volume, cramps, tetany, paresthesias, seizures
Respiratory Alkalosis (cont) Treatment: –Reassurance –Sedation –Pain medication –Rebreathe CO 2 –Reduce ventilator settings to decrease RR and tidal volume
Metabolic Acidosis Loss of Base –Diarrhea –Pancreatic drainage –Renal disease –Fistula Increased Acids –DKA –Salicylate overdose –Sepsis/lactic acidosis –Renal failure –starvation
Metabolic Acidosis (cont) Sx: decreased mental status, confusio, seizures, fatigue, drowsiness, hypotension, anorexia, vomiting, nausea Treatment –Treat the underlying cause –In severe cases, Sodium Bicarbonate may be ordered
Metabolic Alkalosis Increase Base –Sodium Bicarbonate administration –Ingestion of alkaloids Decreased Acids –Vomiting –NG tube suctioning –Electrolyte imbalance
Metabolic Alkalosis (cont) Treatment –Treat the underlying cause –Administer acid (ammonium clloride –Increase bicarbonate excretion with Diamox –In severe cases, dialysis may be ordered
Bronchoscopy
Thoracentesis