YOU CAN DISCOVER YOUR HIDDEN BEAUTY WITH BELLAST, YOU CAN DISCOVER YOUR HIDDEN BEAUTY BELLAST Series consists of Bellast, Bellast Soft, Bellast L24 and Bellast Vital. These products are made of a sterile gel of cross-linked hyaluronic acid, which is non-animal origin. They have biocompatibility to human body and degrade natually over time. They can be used to improve facial wrinkles & folds and maintain elasticity of skin.

BELLAST SERIES : Product Overview BELLAST series is composed of the products for facial beauty treatment. Each product is designed to help you to rejuvenate by filling wrinkles and folds, have edgy facial contour, create volume in which you want to and glowing complexion to look younger and healthier. You can choose the product depending on where you want to treat.

BELLAST SERIES : Product Overview Bellast was the first hyaluronic acid product from Dongkook, and acquired CE mark for the first time in Korea. It is designed to fill medium size and deep wrinkles the face by injection into the middle part of the dermis layer. Bellast Soft is used to fill fine wrinkles and facial lines (such as crow’s feet or perioral wrinkles) by injection into the superficial to mid dermis. Bellast L24 is suitable for use in the filling of moderate to severe facial wrinkles (such as nasolabial folds) by injection into the mid to deep dermis. The presence of Lidocaine is meant to reduce the patient’s pain during treatment. Bellast Vital can create a glowing complexion to look moist and healthy by injection into superficial dermis layer

Indications Medium size and deep wrinkles of face Mid dermis layer Product Recommended indications Where to inject Bellast Medium size and deep wrinkles of face Mid dermis layer Bellast Soft Fine wrinkles and facial lines such as crow’s feet or perioral wrinkles Superficial dermis to mid dermis layer Bellast L24 Moderate to severe facial wrinkles and folds such as nasolabial folds Mid to deep dermis layer Bellast Vital Glowing complexion Superficial dermis layer

Composition Product Composition Packing unit Bellast Each mL contains 20 mg of Cross-linked hyaluronic acid 1.0 mL or 0.6mL / pack Bellast L24 24 mg of Cross-linked hyaluronic acid and 3 mg of Lidocaine hydrochloride Bellast Soft 18 mg of Cross-linked hyaluronic acid Bellast Vital 15 mg of Cross-linked hyaluronic acid 2.0 mL / pack

Advantages HCXL (High concentration cross-linking) Technology Common cross-linking system (Low cross-linking efficacy) BELLAST cross-linking system (High cross-linking efficacy) Based on DK’s own HCXL (High concentration cross-linking) Technology, BELLAST contains a high purity HA Hydrogel of high cross-linking efficacy which is made with minimum cross-linker (BDDE).

Advantages Rheology property : Viscosity and Elasticity   Product A Product B Bellast Bellast L24 Bellast Soft Bellast Vital Shear Viscosity 1200-1300 Pas 200-300 Pas 300-350 Pas 500-700 Pas 100-130 Pas Elastic Modulus 30-45 Pa 130-160 Pa 50-100 Pa 150-250 Pa 20-30 Pa By maintaining the relevant ratio of Viscosity to Elasticity, BELLAST is designed to minimize a possible side effect such as gel migration or easy modification in tissue in case that there is not proper balance between the elasticity and the viscosity.

Advantages Efficacy Total wrinkle area (mm2), percentage of wrinkle area(%) and amount of wrinkles(%) were analyzed before the injection, for 3 months and 6 months after injection. In all test groups and control groups, the depth and amount of wrinkles were decreased in the injection site, and similar to UV negative group.

Advantages Durability From a week after injection, the skin thickness and volume of residual filler were measured once a week, and as a result, filler volume lasted for 6 months in every test groups and control groups. Duration time depends on the injection site, the product to be chosen, or the patient’s condition, but it lasts for up to 6 months in most cases.

Advantages Proved efficacy and safety by clinical study BELLAST is proved to be the effective and safe medical device for the improvement of facial wrinkles such as nasolabial folds by clinical study. Wrinkle Severity Rate Scale (WSRS) after 24 weeks   Treatment group Control group Week 0 Week 24 FA set (n=72) Mean ± SD Min-Max 3.43 ± 0.50 3-4 2.22 ± 0.98 1-4 2.28 ± 0.97 PP set (n=58) 3.41 ± 0.50 2.10 ± 0.97 2.14 ± 0.98 ⇒ Bellast was demonstrated to show the equivalent efficacy to the control group after 24 weeks. * A randomized, multi-center, single blind, matched pairs, active-controlled design clinical study

Advantages Proved efficacy and safety by clinical study BELLAST is proved to be the effective and safe medical device for the improvement of facial wrinkles such as nasolabial folds by clinical study. Frequency of adverse events (n=72)   Treatment Control Treatment + Control Area other than T&C applied sites Total N N(%) Adverse event 10 13 21 1 45 Serious adverse event Withdrew due to adverse event ⇒ All observed adverse events were mild, and there was no subject who experienced serious adverse events or who was withdrawn from the clinical study due to the adverse events. * A randomized, multi-center, single blind, matched pairs, active-controlled design clinical study

Bellast Bellast Soft Bellast L24 History of Development Launched in 2011 Acquired ISO certificate in 2009 Acquired CE certificate in 2010 Completed clinical trial in 2011 Bellast Launch in 2014 Acquired CE certificate in 2013 Bellast Soft Due to launch in 2015 Completed its clinical trial in February, 2014 Due to acquire CE certificate in 2016 Bellast L24

ISO Certificate

CE mark for Bellast

CE mark for Bellast Soft