Histone Modifications and Chromatin Remodeling during Bacterial Infections Mélanie Anne Hamon and Pascale Cossart Cell Host & Microbe Volume 4, Issue.

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Presentation transcript:

Histone Modifications and Chromatin Remodeling during Bacterial Infections Mélanie Anne Hamon and Pascale Cossart Cell Host & Microbe Volume 4, Issue 2, 14 August 2008, Pages Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails Yi Zhang and Danny Reinberg Genes & Dev : Histone modifications Histone methylation Protein Ubiquitination (or Ubiquitylation) (SAM)(SAH)

Wnt signalling in stem cells and cancer Tannishtha Reya and Hans Clevers Nature 434, (14 April 2005) Wnt signalling pathway DotCom mediated H3K79me3

Size exclusion chromatography

Multidimensional LC Separations in Shotgun Proteomics Akira Motoyama Anal. Chem., 2008, 80 (19), pp 7187–7193 MudPIT (Multidimensional Protein Identification Technology)

siRNA-mediated KO

The art and design of genetic screens: Drosophila melanogaster Daniel St Johnston Nature Reviews Genetics 3, (March 2002) UAS-GAL4 system