SAP mediates specific cytotoxic T-cell functions in X- linked lymphoproliferative disease by Reza Sharifi, Joanna C. Sinclair, Kimberly C. Gilmour, Peter.

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Presentation transcript:

SAP mediates specific cytotoxic T-cell functions in X- linked lymphoproliferative disease by Reza Sharifi, Joanna C. Sinclair, Kimberly C. Gilmour, Peter D. Arkwright, Christine Kinnon, Adrian J. Thrasher, and H. Bobby Gaspar Blood Volume 103(10): May 15, 2004 ©2004 by American Society of Hematology

IFN-γ expression by PBMCs from controls and XLP patients following stimulation. Reza Sharifi et al. Blood 2004;103: ©2004 by American Society of Hematology

IFN-γ expression by EBV–T-cell lines from controls and XLP patients following stimulation. Reza Sharifi et al. Blood 2004;103: ©2004 by American Society of Hematology

Cell surface expression of SLAM and 2B4 on EBV–T-cell lines. Reza Sharifi et al. Blood 2004;103: ©2004 by American Society of Hematology

eGFP and SAP expression following retroviral transduction of EBV–T-cell lines from XLP patients. Reza Sharifi et al. Blood 2004;103: ©2004 by American Society of Hematology

EBV–T-cell line cytotoxicity against autologous LCL in controls and XLP patients. Reza Sharifi et al. Blood 2004;103: ©2004 by American Society of Hematology