DNA Bricks Ke, Y., Ong, L. L., Shih, W. M. & Yin, P. Three-dimensional structures self- assembled from DNA bricks. Science 338, 1177–1183 (2012).

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Presentation transcript:

DNA Bricks Ke, Y., Ong, L. L., Shih, W. M. & Yin, P. Three-dimensional structures self- assembled from DNA bricks. Science 338, 1177–1183 (2012).

Prior DNA Nanostructures

Legos Modular Assembly Fixed number of part types that interconnect

DNA Bricks d

DNA Brick Self-Assembly

Using DNA Bricks to Assemble 2D Nanostructures =>

How to use DNA Bricks to Assemble 3D Nanostructures?

=>

DNA Helices composing 3D Cube

Assembly of 3D Cube from DNA Bricks

Details of Assembly of 3D Cube from DNA Bricks

Assembly General 3D Shapes from DNA Bricks

Experimental Results Design AFM Imaging

DNA Bricks design AFM imaging