Ppt on biopotential signals

BME REC BM 2251-BIO MEDICAL INSTRUMENTATION G.THIYAGARAJAN G.THIYAGARAJAN BM17-Lecturer BM17-Lecturer Department of Biomedical Engineering Department.

The electric Model BME REC Motion Artifacts BME REC Biopotential Electrodes BME REC Biopotential electrodes BME REC Suction Electrode BME REC Floating /Electrodes BME REC Flexible Electrodes BME REC Internal Electrodes BME REC Electrode Arrays BME REC Saturated Calomel Electrode BME REC Microelectrodes Microelectrodes Amplifier An amplifier or simply amp, is any device that changes, usually increases, the amplitude of a signal. The "signal/


THE UNIVERSITY OF BRITISH COLUMBIA Multimodal Design & Technologies Sidney Fels.

channel, haptic (touch) channel taste and smell channels Output intentional –neuromuscular, movable, verbal non-intentional / biopotentials –galvanic skin response, heart rate, brain, muscle activation Fels: Multimodal Design and Technologies 7 Human Information Processing/ social loading: intentional, socially invasive and committing gesture and expression: convey functional and emotional signals through touching Fels: Multimodal Design and Technologies 59 motivations for touching we touch intending to /


By: Engr. Hinesh Kumar. Course Outline Introduction to various Physiological Parameters Introduction to Biomedical Instrumentation (BMI) System Transducers/Sensors.

Introduction to Biomedical Instrumentation (BMI) System Transducers/Sensors The Origin of Biopotentials Biopotential Electrodes The Heart & Electrocardiogram (ECG) Biopotential Amplifiers Defibrillators & Pacemakers Measurement of Blood Pressure & Heart Sound Measurement of/blood, which serves as a "transportation system" to transfer oxygen, nutrients, waste products, immune cells, and signalling molecules (i.e., hormones) from one part of the body to another. Respiratory System The respiratory system /


Biomedical Instrumentation I

T wave Q is not as affected because the left bundle branch initiates depolarization Normal Other ECG Signals Interdigital ECG: Signal taken between 2 fingers usually for home monitoring Esophageal ECG: electrode placed in esophagus close to / which cause magnitudes much greater than biopotential signal (ECG) which saturates the amplifier Once the voltage transient signal is removed the ECG signal takes time to recover Example of bandwidth and magnitude of various biopotentials ECG is approximately 1 mV and /


Mai Mohamed Project Team Brain Computer Interface Mohamed Omar Mohamed Sami Nada Mohamed Ahmed Mamdoh

want –Without recognition errors –Whenever you want Physiological problems –No thought sensor –Partial brain knowledge –Noisy signals Solutions in the BCI community ( reality ) –Limited thought –Limited recognition accuracy http://bci2.k-space/Isolation Electrode Isolation Electrode Isolation Electrode Isolation Electrode Isolation Matlab Workspace http://bci2.k-space.org Biopotential Sensors  Electrodes are Biopotential sensor.  There are different types of electrodes: 1. Gold electrode. 2. Silver /


Design of a Novel Efficient Human–Computer Interface: An Electrooculoagram Based Virtual Keyboard 出處 : IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,

SYSTEM(6) NEW EOG-BASED SYSTEM(7) NEW EOG-BASED SYSTEM(8) NEW EOG-BASED SYSTEM(9)  EOG signal measurements are easier than EEG signal measurements. Because EOG signals are caused by muscle motions  In the design of biopotential measurement systems, to reject the common-mode signal 4.RESULTS AND DISCUSSION  Although EEG-based HCI systems are common, they are expensive, inefficient, and impractical, compared/


1 ELEC ENG 4BD4 Lecture 1 Biomedical Instrumentation Instructor: Dr. H. de Bruin.

Noise; Dithering; 5.Digital to Analog converters; Analog to digital converters 10 Laboratory Sessions: Lab 1 : Differential amplifiers; DAQ / DSP / Statistical Analysis Key Concepts: Discrete Signals, Acquisition, Amplifiers, Frequency Domain Lab 2 : ECG / Heart Rate Key Concepts: Biopotentials, Electrocardiogram, Einthovens Triangle, Noise Artifact, Bio-instrumentation amplifier for ECG Lab 3 : EEG Key Concepts: Alpha & Beta Waves (Alpha Blockers) – in phase or out/


1 ELEC ENG 4BD4 Lecture 1 Biomedical Instrumentation Instructor: Dr. Hubert de Bruin de Bruin EE 4BD4 2014.

and Safety Codes Lecture 27Electrical Safety I Lecture 28Electrical Safety II 11 Laboratory Sessions: Lab 1 : Differential amplifiers; DAQ / DSP / Statistical Analysis Key Concepts: Discrete Signals, Acquisition, Amplifiers, Frequency Domain Lab 2 : ECG / Heart Rate Key Concepts: Biopotentials, Electrocardiogram, Einthovens Triangle, Noise Artifact, Bio- instrumentation amplifier for ECG Lab 3 : EEG Key Concepts: Alpha & Beta Waves (Alpha Blockers) – in phase or out/


ENTC 4350 MEDICAL INSTRUMENTATION TRANSDUCERS AND AMPLIFIERS.

which the output voltage is proportional to the difference between two input voltages. Diff amps are particularly useful for measuring biopotentials, because many biopotentials of clinical and medical diagnostic significance consist of the difference in voltage on two body sites. The EEG is the/ of the V OUT due to a voltage when presented to the amplifier as a common-mode signal to the V OUT due to the same signal presented as a difference voltage. This CMRR is often given in decibels (dB) and would have/


Waleed Abdel Aziz Salem, PhD. Electrical Department Benha Faculty of Engineering, Benha University E472 E472 Hospital Instrumentation.

: Excite the muscle cells of the ventricles The contaraction of many muscles cells at one time creates electrical signal that can detected by electrodes Sequence: Depolarization occurs in the sinoatrial (SA) node; current travels through internodal/ cause magnitudes much greater than biopotential signal (ECG) which saturates the amplifier Once the voltage transient signal is removed the ECG signal takes time to recover Example of bandwidth and magnitude of various biopotentials ECG is approximately 1 mV /


BIOMEDICAL ENGINEERING A New, Promising Interdisciplinary Field Mohamed Bingabr, Ph.D. Associate Professor Department of Engineering and Physics University.

of human biomedical functions to different bioengineering applications BME COURSES AT UCO Biomedical Instrumentation (3) –Sensors and Principle –Amplifier and Signal Processing –Origin of BiopotentialBiopotential Electrode and Amplifier –Clinical Laboratory Instrument –Therapeutic And Prosthetic Devices BME COURSES AT UCO Medical Imaging (3) –Signals and Systems –Image Quality –Physics of Radiography –Projection Radiography –Physics of Magnetic Resonance –Magnetic Resonance Imaging BME COURSES AT UCO/


Part 1. General Instrumentation Concepts Reading Assignment: Chapter 1 in our textbook.

Vo/2 - Interfering and Modifying Inputs, Cont’d Temperature, Age, etc. Practical Signal Notch (Band Reject) Filtering Example 60 Hz ac power-line interference is always present in indoor biopotential measurements. In special situations, this kind of interference can be neglected, but this/and expensive) to isolate the subject of measurement from electrical fields produced by a power line. In human biopotential recordings, it is common practice to apply a 50/60 Hz notch filter to reduce this kind of /


A Study of Electrical Impedance Property of an L 2 ePt Electrode 1 Interdisciplinary Program, Bioengineering Major, Graduate School, Seoul National University,

increased nearly 200-fold. (b) Ag/AgCl and L2ePt electrode impedances show similar impedance ranges for the two groups.  In human-machine interface studies and clinical researches, measuring high quality biopotential signals is critical for analyzing functional status of a subject.  But, conventional wet electrodes are uncomfortable and difficult to use in electroencephalogram applications. Also, dry passive electrodes have significant noise problem/


Advanced GEMS MONTUESWEDTHURFRI 8:00 - 8:30Set-up, arrivals, attendance, projects, games, notebooks, checking plates…. 8:30-9:00 Introduction and Evaluations.

. & Catapults during wait times 12:30 - 2:15 Electrophysiology with an invertebrate model: Anesthetized crickets, biopotentials, signal generation, observe responses. S. design exp w/ phone apps Comparative heart anatomy & dissections. Dissect examples / S. dissect/compare 2, 3 & 4 chamber hearts, squid, dogfish shark, sheep Electrophysiology Anesthetized crickets, biopotentials, signal generation, observe responses. S. design experiments w/ phone apps Entomology Dr. Rowton, Guest Speaker. Display, handling/


BME 462 Electrode selection, testing and placement Zexi Liu, Ashley Mulchrone, Yue Yin 09/30/2014.

Yue Yin 09/30/2014 Electrode Selection Dry-Contact and Noncontact Biopotential Electrodes:Methodological Review, Yu Mike Chi etc. Wet Electrode Reusable Low-cost Produce reliable signals in different conditions Adhesive material to lower skin impedance, buffer electrode/ artifact Ex. Polysiloxane framework with conductive nano-particle Non-contact Electrode Dry-Contact and Noncontact Biopotential Electrodes:Methodological Review, Yu Mike Chi etc. Gap between skin and sensor No dielectric layer Measure through/


Course module description:

the calibration factor and write the relation between the input and output Types of Signals Signals can be categorized in several ways, but the most fundamental is according to time/ من 0.05 حتى 10 ميكرومتر معدن عازل زجاج الرأس مايكروإلكترود معدنى Metal Microelectrode الرأس 1 ميكرون محلول ملحى KCl المايكروأنبوبة Micropipette أنبوبة شعرية زجاجية The equivalent circuit for a biopotential electrode. The circuit model of surface electrode contains Op-amp (difference) ,, so that the half cell potential of each/


bioMEDical Instrumentation system

some applications. Generalized Medical Instrumentation System Components of Medical Instrumentation System Measurand Sensor / Transducer Signal Conditioning Output Display Auxiliary Components Measurand The physical quantity, property, or condition that the system/ as Blood or a Biopsy) Cont… Most medically important measurands can be grouped in the following groups: Biopotential, Pressure, Flow, Dimensions (Imaging), Displacement (Velocity, Acceleration, And Force), Impedance, Temperature, And Chemical /


Outline Motivation and Curriculum Goals Overall Structure of Proposed Curriculum Today: Focus on two Sophomore Courses Why? What is in the two new courses?

amplifier - Active filters vs. passive filters ECE concepts involved in doing this lab: How do I get the amplified EKG signal into a computer? - Embedded systems - Data acquisition, analog-to-digital conversion - Sampling rate, Nyquist rate, ADC bit-/ design and analysis 8.Basic neuron physiology, sources of biopotentials, nervous system organization and the cardiac cycle. Analysis of EKG signals. Normal and abnormal frequency content of EKG signals. 9.Design, build, characterize and test a differential /


Outline Motivation and Curriculum Goals Overall Structure of Proposed Curriculum What is in the two new courses? Transition Plan.

Capstone ICapstone II Electronics II Wireless Communication Real Time Embedded Systems Electronics I Power and Energy Discrete Time Signal Processing Embedded Systems Computer Networks +5 General Electives, + 2-3 Technical Electives (Can include CE /design and analysis 8.Basic neuron physiology, sources of biopotentials, nervous system organization and the cardiac cycle. Analysis of EKG signals. Normal and abnormal frequency content of EKG signals. 9.Design, build, characterize and test a differential/


BME 353E – Biomedical Instrumentation & Measurements Instrumentation Basics.

concentrations in the cells”? 5 Ekim 2015 BME 353 - Biomedical Instrumentation and Measurement 7 Medically important measurands Biopotentials Pressure Flow Dimensions (imaging) Displacement (velocity, acceleration and force) Impedance Temperature Chemical concentrations 5 Ekim /Measurement 26 Static sensitivity 5 Ekim 2015 BME 353 - Biomedical Instrumentation and Measurement 27 Sensor signal Measurand Sensor signal Measurand A low-sensitivity sensor has low gain A high sensitivity sensor has high gain Static/


Sensors.

of the measurement time. Resolution: The resolution of a sensor is defined as the minimum detectable signal fluctuation. Since fluctuations are temporal phenomena, there is some relationship between the timescale for the fluctuation and/field sensor (with a relatively lower sensitivity) available what other biomedical application would you think of (other than biopotential measurements). Problem (5) Describe one “innovative” sensor and matching instrumentation for recording breathing or respiration. The /


bioMEDical Instrumentation system

some applications. Generalized Medical Instrumentation System Components of Medical Instrumentation System Measurand Sensor / Transducer Signal Conditioning Output Display Auxiliary Components Measurand The physical quantity, property, or condition that the system/ as Blood or a Biopsy) Cont… Most medically important measurands can be grouped in the following groups: Biopotential, Pressure, Flow, Dimensions (Imaging), Displacement (Velocity, Acceleration, And Force), Impedance, Temperature, And Chemical /


Biomedical Instruments Design 475 BMIS. Medical Instrumentation Design of instrument must match Measurement needs (environmental conditions, safety, reliability,

signal processing output display storage transmission Measurand: Physical quantity, property or condition that the system measures Types of biomedical measurands Internal – Blood pressure Body surface – ECG or EEG potentials Peripheral – Infrared radiation Offline – Extract tissue sample, blood analysis, or biopsy Typical biomedical measurand quantities Biopotential, pressure, flow, dimensions (imaging), displacement (velocity, acceleration and force), impedance, temperature and chemical concentration/


BME 311: BIOMEDICAL INSTRUMENTATION I Lecturer: Ali Işın Lecture Note 1: Introduction to Instrumentation and Measurement Systems BME 311 LECTURE NOTE 1.

2014 important physiological parameters recorded parameters related to cardiovascular dynamics: – blood pressure – blood flow – blood volumes, cardiac output biopotentials: – electrocardiogram (ECG), – electroencephalogram (EEG), – electromyogram (EMG) respiratory parameters: – lung volumes and capacities, – air / or acoustical Auxiliary elements – Data storage – Data transmission – Control and feedback – Calibration signal BME 311 LECTURE NOTE 1 - ALİ IŞIN, 2014 …Generalized Medical Instrumentation System…/


Introduction to the methodology of EEG recording

For Complex Systems and Brain Sciences Florida Atlantic University tognoli@ccs.fau.edu Summary A. Generators and modulators of EEG signal B. Understanding instrumentation C. Main ethical issues D. Physiological and electronical sources of noise E. Constraints for experimental/steady potential (bi-layer, capacitance) This steady potential hampers the movement of the charges This is important since the biopotential we intend to measure is in the range of 1/1000 of the half-cell potential (local potential at /


Sensors p.1ECE 480, Prof. A. Mason SENSORS a.k.a. Interfacing to the Real World: Review of Electrical Sensors and Actuators Andrew Mason Associtate Professor,

amplifier –amplifies only the differential component high common mode rejection ratio –high input impedance suitable for biopotential electrodes with high output impedance input stage gain stage total differential gain Sensors p.18ECE 480, Prof/parameter changes –cross parameter sensitivity: secondary output variation with, e.g., temperature Calibration = adjusting output to match parameter –analog signal conditioning –look-up table –digital calibration T = a + bV +cV 2, –T= temperature; V=sensor voltage; –/


Problem Statement and Motivation Key Achievement and Future Goals Technical Approach Investigators: M. Stroscio, ECE and BioE; M. Dutta, ECE Prime Grant.

affect protein’s mechanical resistance. Goal: Computationally design protein molecules with specific mechanical properties for bio-signaling and bio-materials. All-atom computational simulation for protein conformational changes – Steered Molecular Dynamics Free energy/preparation cultured on a 60-channel multielectrode array, and integrating wind and GPS information. A four-channel biopotential amplifier was constructed to measure the electroantennogram (EAG) from four species of antennae in an air- /


Problem Statement and Motivation Key Achievements and Future Goals Technical Approach Michael Cho, Ph.D. Bioengineering Grant Support: National Institutes.

preparation cultured on a 60-channel multielectrode array, and integrating wind and GPS information. A four-channel biopotential amplifier was constructed to measure the electroantennogram (EAG) from four species of antennae in an air- / affect protein’s mechanical resistance. Goal: Computationally design protein molecules with specific mechanical properties for bio-signaling and bio-materials. All-atom computational simulation for protein conformational changes – Steered Molecular Dynamics Free energy/


Integrating Nanostructures with Biological Structures Investigators: M. Stroscio, ECE and BioE; M. Dutta, ECE Prime Grant Support: ARO, NSF, AFOSR, SRC,

Hongbin Li (U of British Columbia) Problem Statement and Motivation Technical Approach Key Achievements and Future Goals Mechanical signals play key role in physiological processes by controlling protein conformational changes Uncover design principles of mechanical protein stability /as the sensor in a hybrid device that is fast, sensitive and highly specific. A four-channel biopotential amplifier was constructed to measure the electroantennogram (EAG) from four species of antennae in an air-stream/


Biomedical Instrumentation I Chapter 7 Bioelectric Amplifiers from Introduction to Biomedical Equipment Technology By Joseph Carr and John Brown.

Equipment Technology By Joseph Carr and John Brown Bioelectric Amplifiers Definition: An amplifier is used to process biopotential –Adjust gain –DC coupled: needed when signal is very slowly changing or is dc i.e. O 2 level may change pressure mmHg per / gain between 1 and 10 where unity or 1 is most common (used for Isolation, buffering and possibly impedance transformation between signal source and readout device) Medium Gain Amplifier: gain between 10 and 1000 used for ECG, EMG etc. High Gain Amplifier:/


Human Brain and Behavior Laboratory Center for Complex Systems and Brain Sciences Introduction to the methodology of EEG recording Friday October 20th.

of the loops in the anatomical networks Changes in the conduction time due to myelinization Change in the amplitude of the signal due to myelinization –Adult Increased variability over 40 Vigilance –Chronopsychology (more details next) –Drugs –Caffeine Body temperature Hormonal/ potential (bi-layer, capacitance) –This steady potential hampers the movement of the charges This is important since the biopotential we intend to measure is in the range of 1/1000 of the half-cell potential (local potential at the/


CSCE555 Bioinformatics Lecture 18 Network Biology Meeting: MW 4:00PM-5:15PM SWGN2A21 Instructor: Dr. Jianjun Hu Course page:

metabolic network in cells … more biological networks Examples of Biological Networks Metabolic Networks Signaling Networks Transcription Regulatory Networks Protein-Protein Interaction Networks 5 Signaling & Metabolic Pathway Network A Pathway can be defined as a modular unit of interacting molecules to fulfill a cellular function. Signaling Pathway Networks ◦ In biology a signal or biopotential is an electric quantity (voltage or current or field strength), caused by/


Electrocardiogram Amplifier Design Using Basic Electronic Parts Background Lecture.

you going to do? Background: What is ECG? –Clinical relevance and importance –Technical challenges in measuring this signal Project description: How will you do the project? –Overview of project stages –Technical principles related to each stage/simultaneously –Involve 12 leads in total (6 frontal + 6 transverse) Concluding Remarks Conclusion: Learning Outcomes 1)Explain biopotential amplifier circuits to others –Their practical importance and technical details –How they can be used for ECG potential /


Biomedical Instruments Design 475 BMIS. Medical Instrumentation Design of instrument must match Measurement needs (environmental conditions, safety, reliability,

signal processing output display storage transmission Measurand: Physical quantity, property or condition that the system measures Types of biomedical measurands Internal – Blood pressure Body surface – ECG or EEG potentials Peripheral – Infrared radiation Offline – Extract tissue sample, blood analysis, or biopsy Typical biomedical measurand quantities Biopotential, pressure, flow, dimensions (imaging), displacement (velocity, acceleration and force), impedance, temperature and chemical concentration/


Electrocardiogram (ECG) PhillipN, (2007) Display device of a medical monitor as used in anesthesia [photograph]. Retrieved from https://en.wikipedia.org/wiki/Monitoring_(medicine)#/media/File:Monitor_(medical).jpg.

of the chambers –Presence of any damage to the heart –Effects of drugs Specifications Input: Voltage (biopotential) Output : –Electronically (display) –Paper Einthoven’s triangle Principles of Operation Kychot (2009), Einthoven Triangle [image].//wiki/Bispectral_index#/media/File:BIS _Monitor-Burst_Suppression.JPG Commercial Examples Defibrillators also have a wave II ECG signal Pollo (2010), Biphasic defibrillator [photograph]. Retrieved from https://en.wikipedia.org/wiki/Defibrillation#/media/File:/


8C120 - 2010 Inleiding Meten en Modellen – 8C120 Prof.dr.ir. Bart ter Haar Romeny Dr. Andrea Fuster Faculteit Biomedische Technologie Biomedische Beeld.

output-voltage source. Any current flowing to the output terminal v o must pass through the output resistance R o. Most bioelectric signals are small and require amplifications 8C120 - 2010 20 transistors 11 resistors 1 capacitor Inside the Op-Amp (IC-chip) 8C120 - 2010/RfRf 100 kW Voltage, V The output of a biopotential preamplifier that measures the electro-oculogram is an undesired dc voltage of ±5 V due to electrode half-cell potentials, with a desired signal of ±1 V superimposed. Design a circuit that/


Electromyography (EMG). Electromyogram  A tracing made with an electromyograph Electromyograph Electromyography (EMG) is a medical technique for measuring.

(detect), amplify, display in graphic form, and record the weak electrical signals generated by the brain  The technique involves the following:  Biopotential pickup: cranial or cerebral surface transducer electrode  EEG signal conditioning: transducer output amplification and filtering (0.1 to 100 Hz)  EEG signal recording: signal displayed on graphic recorder, CRT or PC  EEG signal analysis: visual or computer interpretation of resulting EEG EEG measurement  Current/


Electrocardiogram Amplifier Design Using Basic Electronic Parts Summary Lecture.

only 0.1 to 5mV in amplitude –Signals often distorted by power-line interference –Poor signal quality  Hard to obtain clinical insights Project Structure Three main stages involved in your project 1.Instrumentation amplifier design 2.Design fine-tuning via conversion to single-supply- driven circuit 3.Multi-lead ECG measurements Learning Outcomes 1)Explain biopotential amplifier circuits to others –Their practical importance/


BY Y.G.MANJUSHA (06071A1011).  A new ENOBIO 4 channel electro physiology device developed by a Star lab.  Features extracted from electroencephalogram.

ECG (Electrocardiogram - heart activity) and EOG (Electrooculogram - eye movement) signals.  The development and first tests of ENOBIO is a dry electrode sensor concept for biopotential applications. In the proposed electrodes the tip of the electrode is covered /ENBIO employs three fundamental enabling aspects to bring electrophysiology into daily life:  Active digital electrodes digitize the signal on site in order to reduce environmental noise  Modular design allows users to customize a single system /


8C120 - 2010 Inleiding Meten en Modellen – 8C120 Prof.dr.ir. Bart ter Haar Romeny Dr. Andrea Fuster Faculteit Biomedische Technologie Biomedische Beeld.

tue.nl Chapter 4-Webster The Origin of Biopotentials 8C120 - 2010 Bioelectric Signals Bioelectrical potential is a result of electrochemical activity across the membrane of the cell. Bioelectrical signals are generated by excitable cells such as nervous,/ by many excitable cells of the specific organ such as the heart. 8C120 - 2010 Typical types of bioelectric signals Electrocardiogram (ECG, EKG) Electroencephalogram (EEG) Electromyogram (EMG) Electroretinogram (ERG) 8C120 - 2010 College 58E020 Inleiding /


What is EEG ? An electroencephalograph (EEG) is the recorded electrical activity generated by the brain. In general, EEG is obtained using electrodes placed.

rubber mesh is used Brain research utilizes even 256 or 512 channel EEG hats Electrodes – Basics High-quality biopotential measurements require – Good amplifier design – Use of good electrodes and their proper placement on the patient – /or irritating Baseline drift due to the changes in junction potential or motion artifacts  Choice of electrodes Muscle signal interference  Placement Electromagnetic interference  Shielding Ag-AgCl, Silver-Silver Chloride Electrodes The most commonly used electrode type/


8C120 Inleiding Meten en Modellen – 8C120 Prof.dr.ir. Bart ter Haar Romeny Faculteit Biomedische Technologie Biomedische Beeld Analyse www.bmia.bmt.tue.nl.

bmt.tue.nl Chapter 4-Webster The Origin of Biopotentials 8C120 Bioelectric Signals Bioelectrical potential is a result of electrochemical activity across the membrane of the cell. Bioelectrical signals are generated by excitable cells such as nervous, / excitable cells of the specific organ such as the heart, or the brain. 8C120 Typical types of bioelectric signals: Electrocardiogram (ECG, EKG) Electroencephalogram (EEG) Electromyogram (EMG) Electroretinogram (ERG) 8C120 Neuron 8C120 Geleidingssysteem van /


P3 Integrated Electronics. DIODES -> Recitifier I If V > V ON of diode, Forward bias, conducting Reverse bias, non conducting I Diodes are silicon based.

IEIE IBIB Base, Emitter, Collector at 27°C Transistors are active components with the ability to amplify electrical signal. Small current at the base B is amplified to produce large current at collector C and emitter E./power, ultra high bandwidth, ultrahigh input impedance Devise different applications for –Integrator (e.g. charge integrator…what sensor? Biopotential measurement.) and Differentiator, Logarithmic amplifier (draw circuits or look up applications in literature) Next, consider an application of/


Example Problem You are measuring the EEG of a patient and accidently choose two different types of electrodes for EEG lead. One of them has a source impedance.

What must the minimum CMRR of the micropipette electrode system be so that an intracellular signal of 50 mV amplitude has no more than 1% common-mode noise? Biopotential Pre-amplifier Preamplifier stage should have a low noise Directly coupled with the electrodes to /of a flashing light, the experimenter finds that the response has approximately the same amplitude as the random noise of the signal. If a signal averager is used, how many samples must be averaged to get an SNR of 20 dB? If we wanted SNR/


April 3 rd, 2008. WIRELESS AUTONOMOUS TRANSDUCER SYSTEMS Sywert H. Brongersma.

Underlying technology to fabricate transducers MEMS, nanowire deposition, micro-optics, … Application layer Algorithmic layer Processing layer Interfacing layer Signal conditioning layer Physical layer Technology layer Picture: P. Nair (Purdue Univ.) An Integrated Approach is Key… © /Telemedical Technology April 3 rd, 2008 < 8< 8 2002: Portable they say… Progress in ambulatory EEG… 2008 ULP biopotential read-out ASIC 3D-SiP layer integration Formfactor 300  1 cm 3 Low power <10mW © Holst Centre Unither /


Biosignals Eugen Kvasnak, PhD. Department of Medical Biophysics and Informatics 3rd Medical Faculty of Charles University.

pathway to the stimulus EPSP a IPSP Synaptic potentials Unit activity vs. Population response Evoked potentials … averaged signal of many cells … recorded from: Cerebral cortex Brainstem Spinal cord Peripheral nerves … Excitable cell: NEURON and/ – electric activity of stomach MagnetoEncephaloGraphy – electric activity of brain... Other Biopotentials? ECG EEG EMG EGG ERG … Temperature Motion pH pO2 Chemicals … Other Signal Sources? Thanks for pictures: R. Hinz, Summer School + other free web sites/


© From J. G. Webster (ed.), Medical instrumentation: application and design. 3 rd ed. New York: John Wiley & Sons, 1998. Figure 6.1 Rough sketch of the.

. 3 rd ed. New York: John Wiley & Sons, 1998. Figure 6.16 Voltage and frequency ranges of some common biopotential signals; dc potentials include intracellular voltages as well as voltages measured from several points on the body. EOG is the electrooculogram, EEG /application and design. 3 rd ed. New York: John Wiley & Sons, 1998. Figure 6.21 Block diagram of an integrator for EMG signals Switch Absolute- value circuit Monostable multivibrator Comparator C EMG Integrator  + R P1P1 v t 11 Counter 22 33/


Different types of normal brain waves Beta waves occur at a frequency of 13 to 30 cycles per second. They are usually associated with anxiety, depression,

rubber mesh is used Brain research utilizes even 256 or 512 channel EEG hats Electrodes – Basics High-quality biopotential measurements require – Good amplifier design – Use of good electrodes and their proper placement on the patient – /or irritating Baseline drift due to the changes in junction potential or motion artifacts  Choice of electrodes Muscle signal interference  Placement Electromagnetic interference  Shielding Ag-AgCl, Silver-Silver Chloride Electrodes The most commonly used electrode type/


Samara 2013 Preclinical research in innovative medicine and biotechnology Dr. Levon Bachdasarian In cooperation with: TNO,Datasciences, The need for multi-modal.

of the hind foot, rubbing the side of the body, neck and face. Locomotion Scratching 16 LABORAS Signal Analog signal form Startle FFT signal Startle LABORAS technique Importance of the enegy parameter in behavioral pharmacology Mv²/2  E k = + δ/ to use animal as its own control or do sequential studies Implantable telemetry Implantable Telemetry Measures combinations of: -Multiple Biopotentials (ECG, EEG, EMG, EOG) -Pressure (Blood Pressure, etc.) -Temperature -Activity Wireless Monitoring of Conscious, Free/


Introduction to Biomedical Sensors BME 301 Biomedical Sensors Lecture Note 1 BME 301 Biomedical Sensors - Ali Işın 2014.

are examples of noncontacting sensors. Noninvasive sensors can also be placed on the body surface like Skin surface thermometers, biopotential electrodes, and strain gauges placed on the skin. BME 301 Biomedical Sensors - Ali Işın 2014 2. / converts force to displacement (mechanical to mechanical) and then an intermediate mechanism to convert displacement to an electrical signal (mechanical to electrical). BME 301 Biomedical Sensors - Ali Işın 2014 Applications Of Biomedical Sensors: Biomedical research/


Ads by Google