1. Nervous System: Part I Introduction to the Nervous System

2. 2 Examine This Image: What body system is shown? Dr. Rufus B. Weaver with Harriet

3. Harriet Dr. Rufus B. Weaver, the school's foremost anatomy professor had a special project in mind for Harriet — a project many colleagues thought impossible. Weaver spent five exhausting months — working eight to 10 hours a day — painstakingly removing every bit of bone and flesh from the cadaver leaving only the nervous system and eyes. 3 Harriet Donated Her Body to Science

4. 4 Animals have nervous systems that detect external and internal signals, transmit and integrate information, and produce responses. What is the function of the nervous system?

5. Role of the nervous system The nervous system interacts with sensory and internal body systems to coordinate responses and behaviors. 5

6. What trends do you notice?

7. Noteworthy Trends In Development Increase in ganglia Increase in sensory reception Increase in cephalization – Cephalization is the concentration of nervous tissue in the anterior region of the organism. 7

8. What would be the advantage of having cephalization? 8 Cephalization supports anterior and sensory input. Bilateral Symmetry = Increased Cephalization

9. Human Nervous System 9

11. 11 Steps in a Reflex Arc

12. Neuron Defined The basic structure of the nervous system that reflects function. The structure of the neuron allows for the detection, generation, transmission, and integration of signal information. 12

13. 13

14. Neuron Neurons are highly specialized for the function of conducting impulses. There are three main types of neurons: – Sensory neurons – Interneurons – Motor neurons 14

15. Where are the neurons in this reflex arc? 15

16. Choose the correct pathway of information flow through neurons while taking a test, starting with reading the question and ending with marking an answer. a. interneurons  motor neurons  sensory neurons  effectors b. effectors  sensory neurons  interneurons  motor neurons c. sensory neurons  interneurons  motor neurons  effectors d. interneurons  sensory neurons  motor neurons  effectors

17. Neuron What are some notable differences between this cell compared to a “typical” animal cell? 17

18. Neuron Anatomy A typical neuron has a cell body, axon and dendrites. 18

19. Label the Diagram in your notes 19 Dendrites Cell Body Nucleus Axon Hillock Axon Axon Terminal

20. Neuron Many axons may have a myelin sheath Myelin Sheath is layer on top of the axon that acts as an electrical insulator. Myelin sheath is produced by a Schwann cell. 20

21. Axon Myelin sheath Schwann cell Nodes of Ranvier Node of Ranvier Layers of myelin Axon Schwann cell Nucleus of Schwann cell 0.1  m

22. Cell body Schwann cell Depolarized region (node of Ranvier) Myelin sheath Axon Saltatory Conduction Saltatory conduction - Notice that the conduction along a myelinated axon can occur quickly as large spaces can be skipped and impulse propagation occurs only at the nodes of Ranvier. Multiple Sclerosis causes demyelination – slower nerve impulses = loss of nerve function

23. POLYSACCHARIDES How are the nerves you saw in Harriet’s picture related to neurons? Nerves are made of bundles of neurons. 23 Putting It All Together