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2003-2004 Immunopharmacology 8 March 2016 7:42 AM.

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Presentation on theme: "2003-2004 Immunopharmacology 8 March 2016 7:42 AM."— Presentation transcript:

1 2003-2004 Immunopharmacology 8 March 2016 7:42 AM

2 Alemtuzumab Antineoplastic Anti-CD52 antibody

3 Aminoglutethimide Antineoplastic Immunosuppressive Glucocorticoid antagonist Aromatase inhibitor (decreases steroid synthesis)

4 Anti-thymocyte globulin Immunosuppressive Anti-T cell antibody

5 Azathioprine Immunosuppressive Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP)

6 Basiliximab Immunosuppressive Anti-CD25 (interleukin 2 receptor) Organ transplant (antirejection)

7 Cyclosporine Immunosuppressive Antineoplastic Binds cyclophilin Inhibits calcineurin

8 Daclizumab Immunosuppressive Anti-CD25 (interleukin 2 receptor) antibody Organ transplant (anti-rejection)

9 Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory steroid Not by inhalation

10 Ibritumomab Antineoplastic Anti-CD20 antibody

11 Interferon alpha Antiviral for hepatitis Antineoplastic Cytokine Anti-angiogenesis

12 Interleukin 2 Cytokine Antineoplastic

13 Interleukin 11 Cytokine Antineoplastic (supporting agent)

14 Methotrexate Immunosuppressive Antineoplastic Folic acid antagonist Dihydrofolate reductase inhibitor

15 Muromonab-CD3 Immunosuppressive Mouse monoclonal anti-CD3 antibody Organ transplant (anti-rejection)

16 Mycophenolate Immunosuppressive Inhibits inosine monophosphate dehydrogenase activity

17 Palivizumab Antiviral Monoclonal antibody against the surface of respiratory syncytial virus

18 Rituxumab Antineoplastic Anti-CD20 antibody

19 Sirolimus Immunosuppressive Binds FKBP, inhibits mTOR (mammalian kinase target of rapamycin) & cell cycle progression Rapamycin

20 Tacrolimus Immunosuppressive Antineoplastic Binds FKBP (FK506 binding protein) Inhibits calcineurin

21 Trastuzumab Antineoplastic Anti-HER2 antibody

22 Tumor necrosis factor  Cytokine Antineoplastic


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