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Death Needs Answers: The DNA Evidence Cybergenetics © 2003-2013 Andrea Niapas Book Launch Pittsburgh, PA May, 2013 Mark W Perlin, PhD, MD, PhD Cybergenetics,

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Presentation on theme: "Death Needs Answers: The DNA Evidence Cybergenetics © 2003-2013 Andrea Niapas Book Launch Pittsburgh, PA May, 2013 Mark W Perlin, PhD, MD, PhD Cybergenetics,"— Presentation transcript:

1 Death Needs Answers: The DNA Evidence Cybergenetics © 2003-2013 Andrea Niapas Book Launch Pittsburgh, PA May, 2013 Mark W Perlin, PhD, MD, PhD Cybergenetics, Pittsburgh, PA

2 Fingernail DNA Evidence 93.3% victim + 6.7% DNA component

3 Three DNA Match Statistics ScoreMethod 13 thousandinclusion 23 millionsubtraction 189 billionaddition Why are there different match results? How do mixture interpretation methods differ? What should be presented in court?

4 DNA cell nucleus chromosomes locus Short Tandem Repeat (STR) genotype 7, 8 alleles

5 D7S820 victim other

6 Different Methods Data Usedinclusionsubtractionaddition victim profile NOYES original data NO YES

7 Threshold: all or none

8 Quantitative: shades of gray

9 Inclusion DNA Match 13 thousand (4)

10 Subtraction DNA Match 13 thousand (4) 23 million (7)

11 Addition DNA Match 13 thousand (4) 23 million (7) 189 billion (11)

12 A Better DNA Microscope "The less informative methods ignored some of the data, while the TrueAllele computation considered all of the available DNA data." "A scientist may look at the same slide using the naked eye, a magnifying glass, or a microscope. A computer that considers all the data is a more powerful DNA microscope."

13 TrueAllele Outcomes TrueAllele admitted, DNA match used at trial Kevin Foley convicted of Dr. Yelenic's murder Sentenced to life imprisonment Appeal denied, Pennsylvania precedent Allegheny County – rape & homicide cases

14 Reducing Rape by DNA Prevention

15 Learn More www.cybgen.com/information Newsletters gentle introduction to ideas Courses for lawyers and scientists Presentations handouts, movies, transcripts Publications magazines, chapters, papers DNA Identification Science

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