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CCystic Fibrosis is an inherited chronic disease IIt affects the lungs and digestive system SSymptoms IIt clogs the lungs with phlegm and causes.

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Presentation on theme: "CCystic Fibrosis is an inherited chronic disease IIt affects the lungs and digestive system SSymptoms IIt clogs the lungs with phlegm and causes."— Presentation transcript:

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2 CCystic Fibrosis is an inherited chronic disease IIt affects the lungs and digestive system SSymptoms IIt clogs the lungs with phlegm and causes life- threatening infections ""obstructs the pancreas and stops natural enzymes from helping the body break down and absorb food." IInteresting Facts CCystic Fibrosis is nicknamed "65 Roses" because children say it that way when they are diagnosed.

3 What Chromosome is Cystic Fibrosis Located On? People with cystic fibrosis inherit a defective gene on chromosome 7 called CFTR (cystic fibrosis transmembrane conductance regulator). The protein produced by this gene normally helps salt (sodium chloride) move in and out of cells. If the protein doesn't work correctly, that movement is blocked and an abnormally thick sticky mucous is produced on the outside of the cell. The cells most seriously affected by this are the lung cells. This mucous clogs the airways in the lungs, and increases the risk of infection by bacteria.

4  This condition is inherited in an autosomal recessive pattern  This means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene  A person gets cystic fibrosis when he or she inherits two mutated CFTR genes; one from each of their parents. The parents don’t have it because they have one dominant allele that isn’t mutated but the child would have the two recessive

5  Alleles are one member of a pair or series of genes that occupy a specific position on a specific chromosome.

6  Top is dad’s genes and left is mom’s. C c C C C c c CCCc cc Cccc C c c


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